Brewers vs. Giants Prediction: San Francisco Predicted to Win Wednesday's MLB Matchup [4/23/2025]

The San Francisco Giants will face the Milwaukee Brewers in MLB action at Oracle Park on Wednesday, starting at 9:45PM ET.

The Giants will have Logan Webb (2-1, 2.40 ERA) as their starting pitcher, while the Brewers will counter with Freddy Peralta (2-1, 1.91 ERA).

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Milwaukee-San Francisco game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Giants' chance of winning at 56%, with the Brewers at 44%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Brewers vs. Giants predictions page.

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Giants vs. Brewers Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Brewers and Giants 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Giants a 56% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 65% chance of covering the run line, while the over/under total of 6.5 runs has a 52% chance of going over.

Pre-Game Probabilities

Last Updated: 1:28AM, Apr 24

Moneyline

Over / Under

Run Line

Brewers

Win %

44%

56%

+125

-142

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Giants

Brewers MIL

+125

Win %

44%

56%

See Matchup

Giants SF

-142

Freddy Peralta 2-1, 1.91 ERA

Logan Webb 2-1, 2.40 ERA

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Brewers vs. Giants Odds [4/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Brewers vs. Giants Picks and Best Bets

Our model's biggest edge in today's Brewers vs. Giants matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Brewers vs. Giants Game-Day Updates and Essential Details

Wednesday's MLB game between the Giants and Brewers at Oracle Park is scheduled to begin at 9:45PM ET.

• Who: Milwaukee Brewers vs. San Francisco Giants
• Date: Wednesday, April 23, 2025
• Time: 9:45PM ET/6:45PM PT
• Venue: Oracle Park

Dimers.com's full preview of Wednesday's Brewers vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Milwaukee vs. San Francisco picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Giants, with a 56% win probability, will likely beat the Brewers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Brewers vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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