Michigan vs. Iowa CFB Predictions and Odds - Dec 4, 2021

Iowa squares off with the favored Michigan in the 2021 Big Ten Football Championship Game at Lucas Oil Stadium on Saturday, starting at 8:00 PM EST.

Dimers' best betting picks for Michigan vs. Iowa, as well as game predictions and best odds, are featured below.

Who will win Michigan vs. Iowa?

Using cutting-edge machine learning and data, Dimers.com has simulated Saturday's Michigan-Iowa NCAA Football matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives Michigan an 83% chance of beating Iowa.

MORE: Full Betting Analysis for Michigan vs. Iowa

Point Spread, Moneyline and Over/Under

Iowa is the +12 underdog versus Michigan, with -110 at Caesars Sportsbook the best odds available.

For the favored Michigan (-12) to cover the spread, Caesars Sportsbook also has the best odds on offer at -110.

FanDuel Sportsbook has the best moneyline odds for Iowa at +410. That means you can throw down $100 to profit $410, earning a total payout of $510, if it wins.

On the other hand, PointsBet has the best moneyline odds for Michigan at -500, where you can risk $500 to win $100, for a total payout of $600, if it comes out on top.

The Over/Under sits at 44 with PointsBet, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out all the legal sportbooks that are available in your state for the best College Football odds and lines.

According to DimersBOT, the bookmakers have got it right and both Michigan and Iowa are a 50% chance of covering the spread, while the 44-point Over/Under is a 51% chance of going Under.

MORE: Predictions for Every CFB Week 14 Game

Best Bets for Michigan vs. Iowa

• Spread: Michigan -12 at -110 with Caesars Sportsbook (50% probability)
• Moneyline: Michigan Win at -500 with PointsBet (83% probability)
• Over/Under: Under 44 at -110 with PointsBet (51% probability)

Michigan vs. Iowa Score Prediction

Dimers.com's predicted final score for Michigan vs. Iowa at Lucas Oil Stadium on Saturday has Michigan winning 28-16.

Use our widget below to see the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Michigan-Iowa matchup, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this article for the latest betting analysis ahead of Michigan vs. Iowa on Saturday December 4, 2021.

Michigan vs. Iowa 2021 CFB Game Info

When does Iowa play Michigan in College Football?

• Date: Saturday December 4, 2021
• Time: 8:00 PM EST / 5:00 PM PST
• Venue: Lucas Oil Stadium

Want to join an online sportsbook and start betting on College Football today? Check out the best sportsbook offers in your state.

What other College Football games are on this week?

Now you've got the 411 on Michigan vs. Iowa, get the latest betting analysis for all upcoming NCAA Football games in Dimers' College Football Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every CFB matchup.

Want a pick for the Spread? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!