Mets vs. Brewers Prediction and Odds - Sep 21, 2022

The Milwaukee Brewers square off with the New York Mets in MLB action at American Family Field on Wednesday, starting at 2:10PM ET.

The Brewers will send Adrian Houser (6-9, 4.85 ERA) to the mound, pitting him against Taijuan Walker (12-4, 3.42 ERA) for the Mets.

Dimers' best betting picks for Mets vs. Brewers, as well as game predictions and best odds, are detailed in this article.

Who will win Mets vs. Brewers?

Based on cutting-edge computer power and data, Dimers.com has simulated Wednesday's Mets-Brewers MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Mets a 54% chance of defeating the Brewers.

More: Mets vs. Brewers Simulated 10,000 Times

Mets vs. Brewers Current Odds

• Run Line: Brewers +1.5 (-142), Mets -1.5 (+125)
• Moneyline: Brewers +118, Mets -135
• Total: Over/Under 8.5 (-120/+105)

Run Line, Moneyline and Over/Under

The Brewers are +1.5 underdogs against the Mets, with -142 at FanDuel Sportsbook the best odds currently available.

For the favored Mets (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +125.

FanDuel Sportsbook currently has the best moneyline odds for the Brewers at +118, which means you can bet $100 to profit $118, earning a total payout of $218, if they win.

Elsewhere, BetMGM currently has the best moneyline odds for the Mets at -135, where you can risk $135 to win $100, for a total payout of $235, if they come out on top.

The Over/Under is set at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -120, while Caesars Sportsbook currently has the best odds for the Under at +105.

As always, check out all of the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Brewers (+1.5) are a 59% chance of covering the run line, while the 8.5-run Over/Under is a 56% chance of going Over.

More: Predictions for Every MLB Game

Best Bets for Mets vs. Brewers

• Run Line: Brewers +1.5 @ -142 via FanDuel Sportsbook (59% probability)
• Moneyline: Brewers @ +118 via FanDuel Sportsbook (0.4% edge)
• Total: Over 8.5 @ -120 via DraftKings Sportsbook (56% probability)

Our best bets are based on world-class simulations and betting expertise to help you make more informed investments with your state's legal sportsbooks.

While the Mets are more likely to win the game, according to DimersBOT, betting on the Brewers moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers is one of the keys to achieving long-term profitability as a bettor.

Mets vs. Brewers Probabilities

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Dimers has full coverage of Wednesday's Mets-Brewers matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates regularly, so keep an eye on this article for the latest betting insights before Mets vs. Brewers on Wednesday September 21, 2022.

Mets vs. Brewers 2022 Game Info

Wednesday's game between the Brewers and Mets at American Family Field is scheduled to commence at 2:10PM ET.

• Who: New York Mets vs. Milwaukee Brewers
• Date: Wednesday September 21, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: American Family Field

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What other MLB games are on today?

The Mets and Brewers aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB game in our MLB Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.