McNeese State vs. Purdue Prediction: Purdue Predicted to Win March Madness Second Round Matchup [3/22/2025]

March Madness action continues on Saturday at 12:10PM ET as McNeese State locks horns with Purdue in college basketball action at Amica Mutual Pavilion.

Based on updated simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Purdue as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities from our expert team.

"Our team has used the latest data to run 10,000 simulations of Saturday's McNeese State-Purdue game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Purdue is more likely to win, while McNeese State has a lower chance of victory."

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive McNeese State vs. Purdue predictions page.

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McNeese State vs. Purdue Prediction: Who Will Win and Advance to the Sweet Sixteen?

Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's NCAA Tournament matchup between McNeese State and Purdue 10,000 times as part of our March Madness predictions coverage.

Our famous predictive model gives Purdue a 76% chance of defeating McNeese State. Our predicted final score has Purdue winning 76-69.

According to our model, Purdue (-6.5) has a 55% chance of covering the spread, while the over/under total of 140.5 points has a 54% chance of going over.

McNeese State vs. Purdue March Madness Odds

We have researched the best March Madness odds in America for this Second Round game, which are listed here:

Bet Type	McNeese State	Purdue
Spread	+6.5 (-112)	-6.5 (-105)
Moneyline	+230	-255
Total	o140.5 (-110)	u140.5 (-105)

All odds are correct at the time of publication and are subject to change.

Boost your betting this month with the top March Madness betting sites and March Madness betting promos, sourced from top sportsbooks and DFS operators.

McNeese State vs. Purdue Picks and Best Bets

Our model's strongest edge in today's McNeese State vs. Purdue matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best March Madness picks and March Madness best bets for every game throughout the tournament.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

McNeese State vs. Purdue Game-Day Updates and Essential Details

Saturday's college basketball game between Purdue and McNeese State at Amica Mutual Pavilion is scheduled to begin at 12:10PM ET.

• Who: McNeese State vs. Purdue
• Date: Saturday, March 22, 2025
• Time: 12:10PM ET/9:10AM PT
• Venue: Amica Mutual Pavilion
• March Madness Stage: Second Round

Dimers.com's comprehensive preview of Saturday's McNeese State vs. Purdue matchup includes our prediction, picks and the latest betting odds.

Before making any McNeese State vs. Purdue picks, be sure to check out the latest March Madness predictions and betting advice from Dimers Pro.

Key March Madness Guides and Insights

• Learn about NCAA Championship history and the lowest-seeded team to ever win March Madness
• Get answers to legal questions, including which states you can legally bet on college sports and the minimum age required to place a bet on March Madness
• A breakdown of March Madness futures bets and popular prop bets for the NCAA tournament
• Explore strategy with guides on identifying value bets during the tournament and betting on individual player awards like Tournament MVP
• Understand the tournament format, including how many games are played in March Madness and how venue locations impact teams when playing at neutral sites

Conclusion

We predict Purdue, with a 76% win probability, will likely beat McNeese State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate McNeese State vs. Purdue insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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