McNeese State vs. Clemson Prediction: Clemson Predicted to Win March Madness First Round Matchup [3/20/2025]

March Madness action continues on Thursday at 3:15PM ET as McNeese State locks horns with Clemson in college basketball action at Amica Mutual Pavilion.

Based on the latest simulation results, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Clemson as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities from our expert team.

"Using the latest data, our experts simulated Thursday's McNeese State-Clemson game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast Clemson with a win probability of 77% and McNeese State with 23%."

For expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive McNeese State vs. Clemson predictions page.

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McNeese State vs. Clemson Prediction: Who Will Win and Advance to the Second Round?

Using powerful machine learning and statistical analysis, we have simulated the result of Thursday's NCAA Tournament matchup between McNeese State and Clemson 10,000 times as part of our March Madness predictions coverage.

Our leading predictive model currently gives Clemson a 77% chance of defeating McNeese State. Our predicted final score has Clemson winning 74-66.

According to our model, the bookmakers have got it right, and McNeese State and Clemson each have a 50% chance of covering the spread, while the over/under total of 136.5 points has a 55% chance of going over.

McNeese State vs. Clemson March Madness Odds

We have sourced the best March Madness odds in America for this First Round game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boost your betting this month with the top March Madness betting sites and March Madness betting promos, sourced from top sportsbooks and DFS operators.

McNeese State vs. Clemson Picks and Best Bets

Our model's biggest edge in today's McNeese State vs. Clemson matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best March Madness picks and March Madness best bets for every game throughout the tournament.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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McNeese State vs. Clemson Game-Day Updates and Essential Details

Thursday's college basketball game between Clemson and McNeese State at Amica Mutual Pavilion is scheduled to start at 3:15PM ET.

• Who: McNeese State vs. Clemson
• Date: Thursday, March 20, 2025
• Time: 3:15PM ET/12:15PM PT
• Venue: Amica Mutual Pavilion
• March Madness Stage: First Round

Dimers.com's full preview of Thursday's McNeese State vs. Clemson matchup includes our prediction, picks and the latest betting odds.

Before making any McNeese State vs. Clemson picks, be sure to check out the latest March Madness predictions and betting advice from Dimers Pro.

Key March Madness Guides and Insights

• Learn about NCAA Championship history and the lowest-seeded team to ever win March Madness
• Get answers to legal questions, including which states you can legally bet on college sports and the minimum age required to place a bet on March Madness
• A breakdown of March Madness futures bets and popular prop bets for the NCAA tournament
• Explore strategy with guides on identifying value bets during the tournament and betting on individual player awards like Tournament MVP
• Understand the tournament format, including how many games are played in March Madness and how venue locations impact teams when playing at neutral sites

Conclusion

We predict Clemson, with a 77% win probability, will likely beat McNeese State on Thursday.

AI and automation have enhanced this article to quickly deliver accurate McNeese State vs. Clemson insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on College Basketball

Keep up with the latest college basketball predictions, college basketball betting news and NCAA Tournament parlay picks throughout the tournament. Plus, our NCAA Tournament Championship odds offer the most accurate predictions for every March Madness contender.