Penrith Panthers vs. Manly Sea Eagles Prediction: Panthers Predicted to Win Saturday's NRL Round 8 Matchup [4/26/2025]

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Written by Jason Bevilacqua

Our expert prediction for Saturday's Penrith Panthers vs Manly Sea Eagles matchup.

Penrith Panthers-Manly Sea Eagles Predictions and Game Preview.
Panthers Stadium sets the stage for the NRL matchup between the Penrith Panthers and Manly Sea Eagles this Saturday.

NRL action continues on Saturday at 5:35AM ET as the Manly Sea Eagles lock horns with the Penrith Panthers at Panthers Stadium.

Based on updated simulations, Dimers' proven NRL model (see Dimers Pro for full access) predicts the Panthers as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Manly-Panthers game," said Pat Sharyon from Dimers.

"By incorporating recent updates and various other inputs, we estimate that the Panthers are more likely to win, while the Sea Eagles have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Sea Eagles vs. Panthers predictions page.

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Panthers vs. Sea Eagles Prediction: Who Will Win Round 8 Game?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NRL game between the Sea Eagles and Panthers 10,000 times as part of our NRL predictions coverage.

Our famous predictive model gives the Panthers a 69% chance of defeating the Sea Eagles.

According to our model, the Panthers (-5.5) have a 56% chance of covering the spread, while the over/under total of 47.5 has a 52% chance of staying under.

Pre-Game Probabilities
Last Updated: 9:45AM, Apr 25
Moneyline
Spread
Over / Under
Sea Eagles
Win %
31%
69%
Get the best bets with Dimers Pro
See Matchup
Panthers
Sea Eagles MAN
Win %
31%
69%
See Matchup
Panthers PEN
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Manly vs. Panthers Odds

We have researched the best NRL odds in America for this game, which are listed here:

Bet Type Sea Eagles Panthers
H2H (Moneyline) +145 -182
Line (Spread) +5.5 (-115) -5.5 (-110)
Total o47.5 (-110) u47.5 (-114)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Panthers vs. Sea Eagles Game-Day Updates and Essential Details

Saturday's Australian rugby league matchup between the Panthers and Sea Eagles at Panthers Stadium is scheduled to begin at 5:35AM ET.

  • Who: Manly Sea Eagles vs. Penrith Panthers
  • Date: Saturday, April 26, 2025
  • Time: 5:35AM ET/2:35AM PT
  • Venue: Panthers Stadium

The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.

Dimers.com's comprehensive preview of Saturday's Sea Eagles vs. Panthers matchup includes our prediction, picks and the latest betting odds.

Before making any Manly vs. Panthers picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.

Conclusion

We predict the Panthers, with a 69% win probability, will likely beat the Sea Eagles on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Sea Eagles vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NRL

Stay up-to-date with the latest NRL betting news and parlay picks throughout the season.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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