Louisville vs. Syracuse CFB Prediction and Odds - Sep 3, 2022

Syracuse faces Louisville in College Football action at JMA Wireless Dome on Saturday, beginning at 8:00PM ET.

Dimers' best betting picks for Louisville vs. Syracuse, as well as game predictions and betting odds, are detailed below.

This Louisville vs. Syracuse betting preview is sponsored by DraftKings Sportsbook, which has a Bet $5, Get $200 promo for new users.

Who will win Louisville vs. Syracuse?

Using high-tech machine learning and data, Dimers.com has simulated Louisville vs. Syracuse 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives Louisville a 64% chance of getting the W against Syracuse.

More: Louisville vs. Syracuse Simulated 10,000 Times

Louisville vs. Syracuse Odds

• Spread: Syracuse +6 (-110), Louisville -6 (-110)
• Moneyline: Syracuse +175, Louisville -192
• Total: Over/Under 55.5 (-106/-110)

Point Spread, Moneyline and Over/Under

Syracuse is listed as the +6 underdog against Louisville, with -110 at Caesars Sportsbook the best odds currently available.

For the favored Louisville (-6) to cover the spread, Caesars Sportsbook also has the best odds currently on offer at -110.

DraftKings Sportsbook currently has the best moneyline odds for Syracuse at +175. That means you can bet $100 to profit $175, earning a total payout of $275, if it wins.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for Louisville at -192, where you can risk $192 to win $100, for a total payout of $292, if it comes out on top.

The Over/Under sits at 55.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -106, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out all of the sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, Syracuse (+6) is a 51% chance of covering the spread, while the 55.5-point Over/Under is a 60% chance of going Under.

More: Free Prop Picks

Best Bets for Louisville vs. Syracuse

• Spread: Syracuse +6 @ -110 via Caesars Sportsbook (51% probability)
• Moneyline: Syracuse @ +175 via DraftKings Sportsbook
• Total: Under 55.5 @ -110 via Caesars Sportsbook (60% probability) 🔥

Every time you see a 🔥, that means you've found one of our best bets of the day across any sport.

Dimers' best bets are based on world-class modeling and wagering expertise to bring you the best possible plays every day of the year.

While Louisville is more likely to win the game, according to DimersBOT, betting on Syracuse moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers is one of the keys to being profitable in the long run.

Louisville vs. Syracuse Score Prediction

Dimers.com's predicted final score for Louisville vs. Syracuse at JMA Wireless Dome on Saturday has Louisville winning 28-23.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Louisville-Syracuse matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this article for the latest betting insights ahead of Louisville vs. Syracuse on Saturday September 3, 2022.

Louisville vs. Syracuse 2022 CFB Game Info

Saturday's matchup between Syracuse and Louisville in College Football at JMA Wireless Dome is scheduled to start at 8:00PM ET.

• Who: Louisville vs. Syracuse
• Date: Saturday September 3, 2022
• Time: 8:00PM ET / 5:00PM PT
• Venue: JMA Wireless Dome

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