Louisville vs. Notre Dame Prediction: Notre Dame Predicted to Win After New Data Released for College Football Week 5 [2024]

Notre Dame and Louisville will clash in college football action at Notre Dame Stadium on Saturday, beginning at 3:30PM ET.

Based on the latest simulation results, Dimers' advanced college football model (see Dimers Pro for full access) predicts Notre Dame as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Louisville-Notre Dame game," said Ryan Leaver from Dimers.

"By incorporating recent updates and various other inputs, we estimate that Notre Dame is more likely to win, while Louisville has a lower chance of victory."

Louisville vs. Notre Dame Game-Day Updates and Essential Details

Saturday's college football matchup between Notre Dame and Louisville at Notre Dame Stadium is scheduled to start at 3:30PM ET.

• Who: Louisville vs. Notre Dame
• Date: Saturday, September 28, 2024
• Time: 3:30PM ET/12:30PM PT
• Venue: Notre Dame Stadium
• Tickets: Get tickets for the game on Ticketmaster

Dimers.com's in-depth preview of Saturday's Louisville vs. Notre Dame matchup includes our prediction, picks and the latest betting odds.

Before making any Notre Dame vs. Louisville picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Louisville vs. Notre Dame Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data analysis, we have simulated the result of Louisville vs. Notre Dame 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Notre Dame a 64% chance of beating Louisville. Our predicted final score has Notre Dame winning 25-21.

According to our model, Louisville (+6.5) has a 55% chance of covering the spread, while the 45-point over/under has a 56% chance of going over.

Pre-Game Probabilities

Last Updated: 1:43PM, Sep 28

Spread

Over / Under

Moneyline

Louisville

Louisville +6.5

55%

45%

+100

-110

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Notre Dame

Louisville LOU

+100

Louisville +6.5

55%

45%

See Matchup

Notre Dame ND

-110

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Louisville vs. Notre Dame Odds

We have researched the best betting odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Louisville vs. Notre Dame Picks

Our model's biggest edge in today's Louisville vs. Notre Dame matchup is on the over/under.

Our expert predictions, aligned with the best odds, reveal the best college football picks for every game throughout the season.

Full access to our picks, including this one, is available via Dimers Pro.

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Conclusion

We predict Notre Dame, with a 64% win probability, will likely beat Louisville on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Notre Dame insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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