Louisville vs. Clemson CBB Prediction and Odds - Jan 11, 2023

Clemson squares off with Louisville in College Basketball action at Littlejohn Coliseum on Wednesday, beginning at 9:00PM ET.

Dimers' best betting picks for Louisville vs. Clemson, as well as our score prediction and best odds, are featured in this article.

Who will win Louisville vs. Clemson?

Using state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Louisville-Clemson College Basketball game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives Clemson a 92% chance of defeating Louisville.

More: Louisville vs. Clemson Simulated 10,000 Times

Louisville vs. Clemson Odds

• Spread: Clemson -16.5 (-110), Louisville +16.5 (-110)
• Moneyline: Clemson -1600, Louisville +1200
• Total: Over/Under 136.5 (-110/-106)

Point Spread, Moneyline and Over/Under

Clemson is the -16.5 favorite versus Louisville, with -110 at PointsBet the best odds currently available.

For the underdog Louisville (+16.5) to cover the spread, PointsBet also has the best odds currently on the market at -110.

PointsBet currently has the best moneyline odds for Clemson at -1600, which means you can risk $1,600 to win $100, for a total payout of $1,700, if it gets the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Louisville at +1200, where you can bet $100 to profit $1,200, earning a total payout of $1,300, if it wins.

The Over/Under sits at 136.5 with PointsBet, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, make sure you check the sportsbooks you can bet with in your state for the best College Basketball odds and lines.

According to DimersBOT, Clemson (-16.5) is a 51% chance of covering the spread, while the Over/Under total of 136.5 points is a 53% chance of going Under.

More: Track Your Bets via Bet Center

Best Bets for Louisville vs. Clemson

• Spread: Clemson -16.5 @ -110 via PointsBet (51% probability)
• Moneyline: Louisville @ +1200 via FanDuel Sportsbook
• Total: Under 136.5 @ -106 via FanDuel Sportsbook (53% probability)

Our best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays 24/7.

While Clemson is more likely to win the game, according to DimersBOT, taking Louisville moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges published here at Dimers is crucial to achieving long-term profitability.

Louisville vs. Clemson Prediction

Dimers.com's predicted final score for Louisville vs. Clemson at Littlejohn Coliseum this Wednesday has Clemson winning 75-59.

Click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Louisville-Clemson matchup, including pregame predictions, free picks, and live updates.

Don't forget, DimersBOT updates often, so keep an eye on this article for any changes to our betting insights before Louisville vs. Clemson on Wednesday January 11, 2023.

Louisville vs. Clemson 2023 CBB Game Info

Wednesday's matchup between Clemson and Louisville in College Basketball at Littlejohn Coliseum is scheduled to start at 9:00PM ET.

• Who: Louisville vs. Clemson
• Date: Wednesday January 11, 2023
• Time: 9:00PM ET / 6:00PM PT
• Venue: Littlejohn Coliseum

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Want more College Basketball previews like this?

So, you liked our Louisville vs. Clemson betting predictions? Awesome. Did you know our College Basketball Betting News page has a detailed betting preview for every CBB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to produce the most accurate CBB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not take a look around?

While you're here, Dimers' CBB Futures page is our in-house approach to determining who will win March Madness 2022, with our data-led probabilities matched against the best odds to win the NCAA Tournament.