Louisiana-Lafayette vs. Southern Miss CFB Prediction and Odds - Oct 27, 2022

Southern Miss squares off with Louisiana-Lafayette in College Football action at M.M. Roberts Stadium on Thursday, beginning at 7:30PM ET.

Dimers' best betting picks for Louisiana-Lafayette vs. Southern Miss, as well as game predictions and betting odds, are featured below.

Who will win Louisiana-Lafayette vs. Southern Miss?

Using cutting-edge machine learning and data, Dimers.com has simulated Louisiana-Lafayette vs. Southern Miss 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives Louisiana-Lafayette a 57% chance of beating Southern Miss.

More: Louisiana-Lafayette vs. Southern Miss Simulated 10K Times

Louisiana-Lafayette vs. Southern Miss Odds

• Spread: Southern Miss +2.5 (-105), Louisiana-Lafayette -2.5 (-107)
• Moneyline: Southern Miss +120, Louisiana-Lafayette -132
• Total: Over/Under 42.5 (-107/-105)

Point Spread, Moneyline and Over/Under

Southern Miss is listed as the +2.5 underdog against Louisiana-Lafayette, with -105 at DraftKings Sportsbook the best odds currently available.

For the favored Louisiana-Lafayette (-2.5) to cover the spread, PointsBet has the best odds currently on offer at -107.

DraftKings Sportsbook currently has the best moneyline odds for Southern Miss at +120, which means you can bet $100 to profit $120, earning a total payout of $220, if it wins.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Louisiana-Lafayette at -132, where you can risk $132 to win $100, for a total payout of $232, if it comes out on top.

The Over/Under for total points scored sits at 42.5 with PointsBet, which currently has the best odds for the Over at -107, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check all the sportsbooks available in your state for the best College Football odds and lines.

According to DimersBOT, the bookmakers have got it right and both Louisiana-Lafayette and Southern Miss are a 50% chance of covering the spread, while the 42.5-point Over/Under is a 59% chance of going Over.

More: Free Online Bet Tracking Tool

Best Bets for Louisiana-Lafayette vs. Southern Miss

• Spread: Southern Miss +2.5 @ -105 via DraftKings Sportsbook (50% probability)
• Moneyline: Louisiana-Lafayette @ -132 via FanDuel Sportsbook (57% probability)
• Total: Over 42.5 @ -107 via PointsBet (59% probability) 🔥

Any time you see a 🔥, you know it's one of our best bets of the day across all sports.

Our best bets are based on complex modeling and betting expertise to serve you the best possible plays 24/7/365.

Louisiana-Lafayette vs. Southern Miss Prediction

Dimers.com's predicted final score for Louisiana-Lafayette vs. Southern Miss at M.M. Roberts Stadium this Thursday has Louisiana-Lafayette prevailing 24-21.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Louisiana-Lafayette-Southern Miss matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this article for any changes to our betting insights before Louisiana-Lafayette vs. Southern Miss on Thursday October 27, 2022.

Louisiana-Lafayette vs. Southern Miss 2022 CFB Game Info

Thursday's game between Southern Miss and Louisiana-Lafayette in College Football at M.M. Roberts Stadium is scheduled to start at 7:30PM ET.

• Who: Louisiana-Lafayette vs. Southern Miss
• Date: Thursday October 27, 2022
• Time: 7:30PM ET / 4:30PM PT
• Venue: M.M. Roberts Stadium

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What College Football games are on this week?

Louisiana-Lafayette and Southern Miss aren't the only two NCAA Football teams you can bet on tonight. DimersBOT never stops and we've got picks and best bets for every single CFB matchup in our College Football Bet Hub section.

Not only do we provide with you quality predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!