Los Angeles Rams vs. San Francisco 49ers Early Predictions for NFL Week 15: Odds, Picks and Preview [2024]

The San Francisco 49ers and Los Angeles Rams are scheduled to meet in Week 15 of the NFL season at Levi's Stadium on Thursday, December 12, 2024, with kickoff set for 8:15PM ET.

Early simulations from Dimers' advanced NFL model favor the 49ers as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Rams vs. 49ers predictions page.

Rams vs. 49ers Week 15 Details

The NFL Week 15 game between the 49ers and Rams at Levi's Stadium is scheduled for December 12, 2024.

• Who: Los Angeles Rams vs. San Francisco 49ers
• Date: Thursday, December 12, 2024
• Time: 8:15PM ET/5:15PM PT
• Venue: Levi's Stadium

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Rams vs. 49ers Opening Odds

We've sourced the best betting odds in America for this Week 15 game, which are listed here:

• Spread: Rams +6.5 (-112), 49ers -6.5 (-108)
• Moneyline: Rams +230, 49ers -285
• Total: Over/Under 47 (-108/-112)

LA Rams vs. San Francisco Early Predictions

Leveraging powerful machine learning and analysis, we have simulated the Rams vs. 49ers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Rams 29%, 49ers 71%
• Predicted Final Score: Rams 20-26 49ers
• Spread: Rams (+6.5) 57%, 49ers (-6.5) 43%
• Total Points (47): Over 49%, Under 51%

As of December 8, 2024, these Rams-49ers predictions reflect the latest data and insights available.

Conclusion

We predict the 49ers, with a 71% win probability, will likely beat the Rams in Week 15 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Rams vs. 49ers matchup, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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