Angels vs. Twins Prediction: Minnesota Predicted to Win Friday's MLB Matchup [4/25/2025]

The Minnesota Twins will face the Los Angeles Angels in MLB action at Target Field on Friday, commencing at 7:40PM ET.

Pablo López (1-1, 1.62 ERA) will be on the bump for the Twins, up against Kyle Hendricks (0-2, 4.50 ERA) for the Angels.

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Twins as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's LA Angels-Minnesota game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Twins' chance of winning is 62%, while the Angels' is 38%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Angels vs. Twins predictions page.

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Twins vs. Angels Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Angels and Twins 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Twins a 62% chance of beating the Angels.

According to our model, the Angels (+1.5) have a 56% chance of covering the run line, while the 8-run over/under has a 53% chance of going over.

Pre-Game Probabilities

Last Updated: 11:28PM, Apr 25

Moneyline

Over / Under

Run Line

Angels

Win %

38%

62%

+175

-132

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Twins

Angels LAA

+175

Win %

38%

62%

See Matchup

Twins MIN

-132

Kyle Hendricks 0-2, 4.50 ERA

Pablo López 1-1, 1.62 ERA

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Angels vs. Twins Odds [4/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Angels vs. Twins Picks and Best Bets

Our model's biggest edge in today's Angels vs. Twins matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Angels vs. Twins Game-Day Updates and Essential Details

Friday's MLB action between the Twins and Angels at Target Field is scheduled to start at 7:40PM ET.

• Who: Los Angeles Angels vs. Minnesota Twins
• Date: Friday, April 25, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's full preview of Friday's Angels vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any LA Angels vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Twins, with a 62% win probability, will likely beat the Angels on Friday.

AI and automation have enhanced this article to quickly deliver accurate Angels vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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