Lions vs. Panthers Week 16 Prediction and Odds - Dec 24, 2022

NFL Week 16 action continues on Saturday at 1:00PM ET as the Detroit Lions lock horns with the Carolina Panthers at Bank of America Stadium.

Dimers' top betting picks for Lions vs. Panthers, as well as game predictions, betting odds and touchdown scorer probabilities, are featured in this article.

Who will win Lions vs. Panthers?

Based on advanced machine learning and data, Dimers.com has simulated Saturday's Lions-Panthers NFL game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Lions a 64% chance of beating the Panthers in Week 16 of the NFL season.

More: Lions vs. Panthers Simulated 10K Times

Lions vs. Panthers Week 16 Odds

• Spread: Panthers +2 (-105), Lions -2 (-107)
• Moneyline: Panthers +115, Lions -120
• Total: Over/Under 43.5 (-107/-107)

Point Spread, Moneyline and Over/Under

The Panthers are +2 underdogs against the Lions, with -105 at DraftKings Sportsbook the best odds currently available.

For the favored Lions (-2) to cover the spread, PointsBet has the best odds currently on offer at -107.

BetMGM currently has the best moneyline odds for the Panthers at +115. That means you can bet $100 to profit $115, earning a total payout of $215, if they win.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Lions at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under sits at 43.5 with PointsBet, which currently has the best odds for the Over at -107, as well as the best odds for the Under at -107.

As always, check out all of the legal sportbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the Lions (-2) are a 58% chance of covering the spread, while the Over/Under total of 43.5 points is considered an equal 50-50 chance of hitting.

More: Predictions for Every NFL Week 16 Game

Best Bets for Lions vs. Panthers

• Spread: Lions -2 @ -107 via PointsBet (58% probability) 🔥
• Moneyline: Lions @ -120 via Caesars Sportsbook (64% probability) 🔥
• Total: Under 43.5 @ -107 via PointsBet (50% probability)

When you see a 🔥, that means it's one of Dimers' best bets today across all major pro and college sports.

Dimers' best bets are based on detailed modeling and wagering expertise to serve you the best possible plays 24/7/365.

Lions vs. Panthers Prediction

Dimers.com's predicted final score for Detroit vs. Carolina at Bank of America Stadium in Week 16 has the Lions prevailing 23-20.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Lions-Panthers matchup in Week 16, including pregame predictions, free picks, and live win probabilities.

Lions vs. Panthers Player Props

Who will score an anytime touchdown in Lions vs. Panthers? The latest data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Lions and Panthers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop bets for Saturday's game.

According to DimersBOT, Detroit's Jamaal Williams is most likely to score the first touchdown in Lions vs. Panthers.

DimersBOT gives Williams a 15.1% chance of scoring the first TD at Bank of America Stadium, while the Lions RB is a 55.4% chance of scoring an anytime touchdown.

Scroll down for our complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Detroit Lions

• Jamaal Williams: 15.1% probability
• Amon-Ra St. Brown: 7.3% probability
• D'Andre Swift: 7.0% probability
• DJ Chark: 5.1% probability
• Josh Reynolds: 4.5% probability

Carolina Panthers

• D'Onta Foreman: 11.5% probability
• DJ Moore: 7.0% probability
• Chuba Hubbard: 6.2% probability
• Laviska Shenault: 5.5% probability
• Terrace Marshall: 4.6% probability

Anytime Touchdown Scorer Probabilities

Detroit Lions

• Jamaal Williams: 55.4% probability
• Amon-Ra St. Brown: 31.4% probability
• D'Andre Swift: 29.5% probability
• DJ Chark: 23.7% probability
• Josh Reynolds: 21.0% probability

Carolina Panthers

• D'Onta Foreman: 46.8% probability
• DJ Moore: 30.0% probability
• Chuba Hubbard: 28.0% probability
• Laviska Shenault: 25.0% probability
• Terrace Marshall: 20.9% probability

Lions-Panthers Projected Player Stats

Of the starting quarterbacks, the Lions' Jared Goff is projected for 259 passing yards, while the Panthers' Sam Darnold is expected to throw for just 171 yards.

Lions Starting QB

• Jared Goff: 259 projected yards

Panthers Starting QB

• Sam Darnold: 171 projected yards

Lions Rushing

• Jamaal Williams: 64 projected yards
• D'Andre Swift: 35 projected yards
• Justin Jackson: 13 projected yards

Panthers Rushing

• D'Onta Foreman: 69 projected yards
• Chuba Hubbard: 37 projected yards
• Sam Darnold: 18 projected yards

Lions Receiving

• Amon-Ra St. Brown: 88 projected yards
• DJ Chark: 42 projected yards
• Josh Reynolds: 31 projected yards
• D'Andre Swift: 30 projected yards
• Brock Wright: 21 projected yards

Panthers Receiving

• DJ Moore: 50 projected yards
• Terrace Marshall: 42 projected yards
• Laviska Shenault: 27 projected yards
• D'Onta Foreman: 17 projected yards
• Ian Thomas: 17 projected yards

Remember, DimersBOT updates regularly, so keep an eye on this page for any changes to our betting analysis ahead of Lions vs. Panthers on Saturday December 24, 2022.

Lions vs. Panthers 2022

The NFL Week 16 game between the Panthers and Lions at Bank of America Stadium is scheduled to begin at 1:00PM ET.

• Who: Detroit Lions vs. Carolina Panthers
• Date: Saturday December 24, 2022
• Time: 1:00PM ET / 10:00AM PT
• Venue: Bank of America Stadium

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What other NFL games are on today?

The Lions and Panthers aren't the only two NFL teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single NFL matchup via our NFL Predictions page.

Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!