Chiefs vs. 49ers Prediction: San Francisco Predicted to Win in NFL Week 7 [2024]

The San Francisco 49ers will take on the Kansas City Chiefs in NFL Week 7 action at Levi's Stadium on Sunday, starting at 4:25PM ET.

Based on updated simulations, Dimers' proven NFL model (see Dimers Pro for full access) projects the 49ers as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Chiefs-49ers game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the 49ers with a win probability of 60%, while the Chiefs have 40%."

Chiefs vs. 49ers Game-Day Updates and Essential Details

The NFL Week 7 matchup between the 49ers and Chiefs at Levi's Stadium is scheduled to begin at 4:25PM ET.

• Who: Kansas City Chiefs vs. San Francisco 49ers
• Date: Sunday, October 20, 2024
• Time: 4:25PM ET/1:25PM PT
• Venue: Levi's Stadium
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy 49ers and Chiefs gear at Fanatics
• Live Stream: Watch this game on FOX via Hulu or FuboTV

Dimers.com's comprehensive preview of Sunday's Chiefs vs. 49ers matchup includes our prediction, picks and the latest betting odds.

Before making any 49ers vs. Chiefs picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Chiefs vs. 49ers Predictions

Using innovative machine learning and statistical analysis, we have simulated the outcome of Sunday's NFL game between the Chiefs and 49ers 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the 49ers a 60% chance of defeating the Chiefs in Week 7 of the NFL season. Our predicted final score has the 49ers winning 24-22.

According to our model, the bookmakers have got it right, and the Chiefs and 49ers each have a 50% chance of covering the spread, while the over/under total of 48.5 points has a 53% chance of staying under.

In addition to our Chiefs vs. 49ers predictions, we've also here's what else we've got for today’s action:

• NFL Best Bets for Week 7
• NFL Player Props for Week 7
• Anytime TD Scorer Predictions for Week 7

Chiefs vs. 49ers Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type	Chiefs	49ers
Spread	+2.5 (-105)	-2.5 (-110)
Moneyline	+122	-135
Total	o48.5 (-105)	u48.5 (-115)

All odds are correct at the time of publication and are subject to change.

Chiefs vs. 49ers Picks

Our model's strongest edge in today's Chiefs vs. 49ers matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

Chiefs vs. 49ers TD Scorers

Who will score an anytime touchdown in Chiefs vs. 49ers?

According to our model, San Francisco's Jordan Mason is most likely to score the first TD in Chiefs vs. 49ers.

Our projections give Mason an 11.6% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 47.7% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Kansas City Chiefs

Player	First TD Probability
Kareem Hunt	9.4%
Travis Kelce	8.8%
Xavier Worthy	6.8%

San Francisco 49ers

Player	First TD Probability
Jordan Mason	11.6%
Deebo Samuel	10.1%
George Kittle	8.9%

Anytime Touchdown Scorer Predictions

Kansas City Chiefs

Player	Anytime TD Probability
Kareem Hunt	41.8%
Travis Kelce	39.5%
Xavier Worthy	31.6%

San Francisco 49ers

Player	Anytime TD Probability
Jordan Mason	47.7%
Deebo Samuel	43.2%
George Kittle	39.2%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 7 touchdown scorer predictions

Chiefs vs 49ers Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Chiefs and 49ers. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Chiefs-49ers page now to access every player prop projection.

Chiefs vs. 49ers Quarterbacks

Of the starting quarterbacks, the Chiefs' Patrick Mahomes is projected to throw for fewer yards than the 49ers' Brock Purdy.

Chiefs Rushing

Kareem Hunt, Patrick Mahomes and Samaje Perine are projected to be the leading rushers for the Chiefs.

Player	Position
Kareem Hunt	RB
Patrick Mahomes	QB
Samaje Perine	RB

49ers Rushing

Jordan Mason, Isaac Guerendo and Deebo Samuel are expected to lead the 49ers in rushing yards.

Player	Position
Jordan Mason	RB
Isaac Guerendo	RB
Deebo Samuel	WR

Chiefs Receiving

Travis Kelce, Xavier Worthy, JuJu Smith-Schuster, Mecole Hardman and Justin Watson are projected to top the receiving yards for the Chiefs.

Player	Position
Travis Kelce	TE
Xavier Worthy	WR
JuJu Smith-Schuster	WR
Mecole Hardman	WR
Justin Watson	WR

49ers Receiving

Brandon Aiyuk, George Kittle, Deebo Samuel, Ricky Pearsall and Jordan Mason are projected to lead the 49ers in receiving yards.

Player	Position
Brandon Aiyuk	WR
George Kittle	TE
Deebo Samuel	WR
Ricky Pearsall	WR
Jordan Mason	RB

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Conclusion

We predict the 49ers, with a 60% win probability, will likely beat the Chiefs on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Chiefs vs. 49ers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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