Jaguars vs. Colts Week 6 Prediction and Odds - Oct 16, 2022

The Indianapolis Colts and Jacksonville Jaguars lock horns in Week 6 of the NFL season at Lucas Oil Stadium on Sunday, with kickoff at 1:00PM ET.

Dimers' best betting picks for Jaguars vs. Colts, as well as game predictions, betting odds and touchdown scorer probabilities, are featured below.

Who will win Jaguars vs. Colts?

Using cutting-edge computer power and data, Dimers.com has simulated Sunday's Jaguars-Colts NFL game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Colts a 57% chance of beating the Jaguars in Week 6 of the NFL season.

More: Full Betting Analysis for Jaguars vs. Colts

Jaguars vs. Colts Game Odds

• Spread: Colts -2 (-110), Jaguars +2 (-105)
• Moneyline: Colts -125, Jaguars +114
• Total: Over/Under 41.5 (-114/-106)

Point Spread, Moneyline and Over/Under

The Colts are currently -2 favorites against the Jaguars, with -110 at Caesars Sportsbook the best odds currently available.

For the underdog Jaguars (+2) to cover the spread, PointsBet has the best odds currently on offer at -105.

PointsBet currently has the best moneyline odds for the Colts at -125. That means you can risk $125 to win $100, for a total payout of $225, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Jaguars at +114, where you can bet $100 to profit $114, earning a total payout of $214, if they win.

The Over/Under is set at 41.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, as well as the best odds for the Under at -106.

As always, check out the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the Jaguars (+2) are a 52% chance of covering the spread, while the Over/Under total of 41.5 points is a 52% chance of going Over.

More: Predictions for Every NFL Matchup

Best Bets for Jaguars vs. Colts

• Spread: Jaguars +2 @ -105 via PointsBet (52% probability)
• Moneyline: Colts @ -125 via PointsBet (57% probability)
• Total: Over 41.5 @ -114 via FanDuel Sportsbook (52% probability)

Our best bets are based on world-class simulations and gambling intelligence to help you make better investments with the legal sportsbooks in the United States.

Jaguars vs. Colts Prediction

Dimers.com's predicted final score for Jacksonville vs. Indianapolis at Lucas Oil Stadium in Week 6 has the Colts winning 21-20.

Click or tap on See Matchup for more.

Dimers has full betting coverage of this week's Jaguars-Colts matchup in Week 6, including pregame predictions, top betting picks, and live win probabilities.

Jaguars vs. Colts Player Props

Who will score an anytime touchdown in Jaguars vs. Colts? The latest data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the Jaguars and Colts, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you choose the best prop picks for Sunday's game.

According to DimersBOT, Indianapolis' Jonathan Taylor is most likely to score the first TD in Jaguars vs. Colts.

DimersBOT gives Taylor a 12.8% chance of scoring the first TD at Lucas Oil Stadium, while the Colts RB is a 48.7% chance of registering an anytime touchdown.

Scroll down for our complete list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Jacksonville Jaguars

• James Robinson: 9.7% probability
• Christian Kirk: 8.5% probability
• Travis Etienne: 7.8% probability
• Zay Jones: 6.5% probability
• Marvin Jones: 5.3% probability

Indianapolis Colts

• Jonathan Taylor: 12.8% probability
• Michael Pittman: 9.3% probability
• Alec Pierce: 6.4% probability
• Nyheim Hines: 6.3% probability
• Mo Alie-Cox: 4.9% probability

Anytime Touchdown Scorer Probabilities

Jacksonville Jaguars

• James Robinson: 40.1% probability
• Christian Kirk: 35.1% probability
• Travis Etienne: 32.7% probability
• Zay Jones: 27.4% probability
• Marvin Jones: 23.3% probability

Indianapolis Colts

• Jonathan Taylor: 48.7% probability
• Michael Pittman: 36.5% probability
• Alec Pierce: 27.8% probability
• Nyheim Hines: 27.4% probability
• Mo Alie-Cox: 21.7% probability

Jaguars-Colts Projected Player Stats

Of the starting quarterbacks, the Jaguars' Trevor Lawrence is projected for 250 passing yards, while the Colts' Matt Ryan is expected to throw for 251 yards.

Jaguars Starting QB

• Trevor Lawrence: 250 projected yards

Colts Starting QB

• Matt Ryan: 251 projected yards

Jaguars Rushing

• James Robinson: 74 projected yards
• Travis Etienne: 36 projected yards
• Trevor Lawrence: 14 projected yards

Colts Rushing

• Jonathan Taylor: 82 projected yards
• Nyheim Hines: 18 projected yards
• Deon Jackson: 17 projected yards

Jaguars Receiving

• Christian Kirk: 69 projected yards
• Marvin Jones: 41 projected yards
• Zay Jones: 38 projected yards
• Evan Engram: 29 projected yards
• Travis Etienne: 22 projected yards

Colts Receiving

• Michael Pittman: 52 projected yards
• Alec Pierce: 46 projected yards
• Kylen Granson: 27 projected yards
• Jonathan Taylor: 24 projected yards
• Mo Alie-Cox: 23 projected yards

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting insights ahead of Jaguars vs. Colts on Sunday October 16, 2022.

Jaguars vs. Colts 2022

The NFL Week 6 matchup between the Colts and Jaguars at Lucas Oil Stadium is scheduled to begin at 1:00PM ET.

• Who: Jacksonville Jaguars vs. Indianapolis Colts
• Date: Sunday October 16, 2022
• Time: 1:00PM ET / 10:00AM PT
• Venue: Lucas Oil Stadium

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