Jacksonville Jaguars vs. Indianapolis Colts Early Predictions for NFL Week 18: Odds, Picks and Preview [2025]

The Indianapolis Colts and Jacksonville Jaguars will meet in Week 18 of the NFL season at Lucas Oil Stadium on Sunday, January 5, 2025, starting at 1:00PM ET.

Early simulations from Dimers' trusted NFL model favor the Colts as the most likely winner of this showdown.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Jaguars vs. Colts predictions page.

Jaguars vs. Colts Week 18 Details

The NFL Week 18 matchup between the Colts and Jaguars at Lucas Oil Stadium is scheduled for January 5, 2025.

• Who: Jacksonville Jaguars vs. Indianapolis Colts
• Date: Sunday, January 5, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium

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Jaguars vs. Colts Latest Odds

We've researched the best betting odds across America for this Week 18 game, which are listed here:

• Spread: Jaguars +4.5 (-106), Colts -4.5 (-114)
• Moneyline: Jaguars +185, Colts -205
• Total: Over/Under 43.5 (-110/-105)

Jacksonville vs. Indianapolis Early Predictions

Leveraging trusted machine learning and analysis, we have simulated the Jaguars vs. Colts game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Jaguars 33%, Colts 67%
• Predicted Final Score: Jaguars 19-24 Colts
• Spread: Jaguars (+4.5) 49%, Colts (-4.5) 51%
• Total Points (43.5): Over 52%, Under 48%

As of January 2, 2025, these Jaguars-Colts predictions reflect the latest data and insights available.

Anytime Touchdown Scorer Predictions

Here are our initial touchdown probabilities for the Jaguars-Colts game:

Jacksonville Jaguars

• Tank Bigsby: 46.9% probability
• Brian Thomas: 39.9% probability
• Travis Etienne: 31.3% probability

Indianapolis Colts

• Jonathan Taylor: 59.5% probability
• Anthony Richardson: 42.5% probability
• Michael Pittman: 28.5% probability

Jaguars vs Colts Player Props

Travis Etienne is projected to lead rushing for the Jaguars, while Jonathan Taylor is expected to pace the Colts on the ground.

In the receiving game, our projections favor Jacksonville's Brian Thomas and Indianapolis' Josh Downs as the likely leaders for each team.

Conclusion

We predict the Colts, with a 67% win probability, will likely beat the Jaguars in Week 18 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Jaguars vs. Colts matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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