Iowa State vs. Oklahoma CFB Predictions and Odds - Nov 20, 2021

Oklahoma and Iowa State meet in Week 12 of the College Football season at Gaylord Family Oklahoma Memorial Stadium on Saturday, starting at 12:00 PM EST.

Dimers' top betting picks for Iowa State vs. Oklahoma, plus our score prediction and best odds, are detailed in this article.

Who will win Iowa State vs. Oklahoma?

Based on cutting-edge machine learning and data, Dimers.com has simulated Saturday's Iowa State-Oklahoma NCAA Football matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives Oklahoma a 59% chance of beating Iowa State.

MORE: Full betting guide for Iowa State vs. Oklahoma

Iowa State vs. Oklahoma Point Spread, Moneyline and Over/Under

Oklahoma is listed as the -3 favorite at home to Iowa State, with -110 at Caesars Sportsbook the best odds available.

For the underdog Iowa State (+3) to cover the spread, DraftKings Sportsbook has the best odds on offer at +100.

PointsBet has the best moneyline odds for Oklahoma at -150, which means you can risk $150 to win $100, for a total payout of $250, if it gets the W.

On the other hand, DraftKings Sportsbook has the best moneyline odds for Iowa State at +140, where you can bet $100 to profit $140, earning a total payout of $240, if it wins.

The Over/Under for total points scored sits at 61.5 with FanDuel Sportsbook, which has the best odds for the Over at -105, as well as the best odds for the Under at -115.

As always, check out the sportsbooks you can bet with in your state for the best College Football odds and lines.

According to DimersBOT, Oklahoma (-3) is a 51% chance of covering the spread, while the Over/Under total of 61.5 points is a 57% chance of going Under.

MORE: Live scores and win probabilities for all major sports

Best Bets for Iowa State vs. Oklahoma

• Spread: Iowa State +3 at +100 with DraftKings Sportsbook
• Moneyline: Iowa State Win at +140 with DraftKings Sportsbook
• Over/Under: Under 61.5 at -115 with FanDuel Sportsbook (57% probability)

Even though Oklahoma is more likely to cover the spread, our best bet of Iowa State +3 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

And while Oklahoma is more likely to win the game, according to DimersBOT, taking Iowa State moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published on Dimers.com is one of the keys to achieving long-term profitability.

Iowa State vs. Oklahoma Score Prediction

Dimers.com's predicted final score for Iowa State vs. Oklahoma at Gaylord Family Oklahoma Memorial Stadium on Saturday has Oklahoma winning 31-28.

Dimers has full betting coverage of this week's Iowa State-Oklahoma game, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep an eye on this article for the latest ahead of Iowa State vs. Oklahoma on Saturday November 20, 2021.

Iowa State vs. Oklahoma 2021 CFB Game Info

When does Oklahoma play Iowa State in College Football?

• Date: Saturday November 20, 2021
• Time: 12:00 PM EST / 9:00 AM PST
• Venue: Gaylord Family Oklahoma Memorial Stadium

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