Houston vs. South Florida CFB Predictions and Odds - Nov 6, 2021

South Florida takes on the favored Houston in College Football Week 10 action at Raymond James Stadium on Saturday, starting at 7:30 PM EDT.

Dimers' free betting picks for Houston vs. South Florida, as well as game predictions and best odds, are detailed in this article.

Who will win Houston vs. South Florida?

Based on high-tech computer power and data, Dimers.com has simulated Saturday's Houston-South Florida game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives Houston a 82% chance of getting the W against South Florida.

MORE: Houston vs. South Florida simulated 10,000 times

Houston vs. South Florida Point Spread, Moneyline and Over/Under

South Florida is the +13.5 underdog against Houston, with -104 at FanDuel Sportsbook the best odds available.

For the favored Houston (-13.5) to cover the spread, Caesars Sportsbook has the best odds on the market at -110.

FanDuel Sportsbook has the best moneyline odds for South Florida at +440. That means you can bet $100 to profit $440, earning a total payout of $540, if it wins.

Meanwhile, PointsBet has the best moneyline odds for Houston at -560, where you can risk $560 to win $100, for a total payout of $660, if it comes out on top.

The Over/Under for total points scored sits at 53 with Caesars Sportsbook, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you can bet with in your state for the best College Football odds and lines.

According to DimersBOT, the bookies have got it right and both Houston and South Florida are a 50% chance of covering the spread, while the 53-point Over/Under is a 54% chance of going Over.

Best Bets for Houston vs. South Florida

• Spread: South Florida +13.5 at -104 with FanDuel Sportsbook (50% probability)
• Moneyline: South Florida Win at +440 with FanDuel Sportsbook
• Over/Under: Over 53 at -110 with Caesars Sportsbook (54% probability)

While Houston is more likely to win the game, according to DimersBOT, betting on South Florida moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges seen on Dimers.com is crucial to achieving long-term profitability.

MORE: Predictions for every College Football Week 10 matchup

Houston vs. South Florida Predicted Score

Dimers.com's predicted score for Houston vs. South Florida at Raymond James Stadium on Saturday has Houston winning 32-18.

Dimers has full coverage of this week's Houston-South Florida game, including pre-game predictions, free picks, live scores, and play-by-play commentary.

Remember, DimersBOT updates often, so keep an eye on this article for any changes ahead of Houston vs. South Florida on Saturday November 6, 2021.

Houston vs. South Florida 2021 CFB Game Info

When does South Florida play Houston?

• Date: Saturday November 6, 2021
• Time: 7:30 PM EDT / 4:30 PM PDT
• Venue: Raymond James Stadium

Looking to join an online sportsbook and start betting on College Football? We've got access to the best available sign-up offers in every legal betting state.

Want more College Football previews like this?

To get more College Football betting previews like this one for Houston vs. South Florida, all you've gotta do is visit Dimers' College Football Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the best CFB betting previews available. We do this by comparing our accurate and powerful probabilities against the sportsbooks' odds as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.