Astros vs. Mariners Prediction: Seattle Predicted to Win Tuesday's MLB Matchup [4/8/2025]

The Seattle Mariners will take on the Houston Astros, in what is expected to be a close MLB game, at T-Mobile Park on Tuesday, commencing at 9:40PM ET.

Luis Castillo (1-1, 3.00 ERA) will be on the bump for the Mariners, while the Astros are going with Framber Valdez (1-1, 3.75 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Houston-Seattle game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Mariners with a win probability of 51%, compared to 49% for the Astros."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Astros vs. Mariners predictions page.

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Astros vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Tuesday's MLB game between the Astros and Mariners 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Mariners a 51% chance of defeating the Astros.

According to our model, the Astros (+1.5) have a 68% chance of covering the run line, while the 7-run over/under has a 52% chance of going over.

Pre-Game Probabilities

Last Updated: 1:28AM, Apr 9

Moneyline

Over / Under

Run Line

Astros

Win %

49%

51%

+115

-120

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Mariners

Astros HOU

+115

Win %

49%

51%

See Matchup

Mariners SEA

-120

Framber Valdez 1-1, 3.75 ERA

Luis Castillo 1-1, 3.00 ERA

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Astros vs. Mariners Odds [4/8/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Astros vs. Mariners Picks and Best Bets

Our model's strongest edge in today's Astros vs. Mariners matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Astros vs. Mariners Game-Day Updates and Essential Details

Tuesday's MLB game between the Mariners and Astros at T-Mobile Park is scheduled to commence at 9:40PM ET.

• Who: Houston Astros vs. Seattle Mariners
• Date: Tuesday, April 8, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: T-Mobile Park

Dimers.com's in-depth preview of Tuesday's Astros vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Seattle picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mariners, with a 51% win probability, will likely beat the Astros on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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