Astros vs. Mariners Prediction: Seattle Predicted to Win Monday's MLB Matchup [4/7/2025]

The Seattle Mariners will face the Houston Astros in the NCAA Championship Game at T-Mobile Park on Monday, beginning at 9:40PM ET.

The Mariners will send Logan Gilbert (0-1, 3.00 ERA) to the mound, up against Hayden Wesneski (0-1, 5.40 ERA) for the Astros.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's Houston-Seattle game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Mariners are likely to win, with a probability of 57%, compared to the Astros' 43%."

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Astros vs. Mariners predictions page.

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Astros vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Monday's MLB game between the Astros and Mariners 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Mariners a 57% chance of defeating the Astros.

According to our model, the Astros (+1.5) have a 63% chance of covering the run line, while the over/under total of 7 runs has a 55% chance of going over.

Pre-Game Probabilities

Last Updated: 3:28AM, Apr 8

Moneyline

Over / Under

Run Line

Astros

Win %

41%

59%

+140

-158

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Mariners

Astros HOU

+140

Win %

41%

59%

See Matchup

Mariners SEA

-158

Hayden Wesneski 0-1, 5.40 ERA

Logan Gilbert 0-1, 3.00 ERA

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Astros vs. Mariners Odds [4/7/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Astros vs. Mariners Picks and Best Bets

Our model's biggest edge in today's Astros vs. Mariners matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Astros vs. Mariners Game-Day Updates and Essential Details

Monday's MLB game between the Mariners and Astros at T-Mobile Park is scheduled to begin at 9:40PM ET.

• Who: Houston Astros vs. Seattle Mariners
• Date: Monday, April 7, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: T-Mobile Park

Dimers.com's in-depth preview of Monday's Astros vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Seattle picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mariners, with a 57% win probability, will likely beat the Astros on Monday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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