Astros vs. Royals Prediction: Houston Predicted to Win Saturday's MLB Matchup [4/26/2025]

The Kansas City Royals and Houston Astros will meet in MLB action at Kauffman Stadium on Saturday, starting at 7:10PM ET.

The Royals will have Michael Wacha (0-3, 4.15 ERA) as their starting pitcher, while the Astros have opted for Framber Valdez (1-2, 4.50 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Astros as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Houston-Kansas City game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Astros are more likely to win, while the Royals have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Astros vs. Royals predictions page.

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Royals vs. Astros Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data analysis, we have simulated the outcome of Saturday's MLB game between the Astros and Royals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Astros a 56% chance of beating the Royals.

According to our model, the Royals (+1.5) have a 57% chance of covering the run line, while the 8-run over/under has a 51% chance of staying under.

Pre-Game Probabilities

Last Updated: 11:27PM, Apr 26

Moneyline

Over / Under

Run Line

Astros

Win %

57%

43%

+165

+120

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See Matchup

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Royals

Astros HOU

+165

Win %

57%

43%

See Matchup

Royals KC

+120

Framber Valdez 1-2, 4.50 ERA

Michael Wacha 0-3, 4.15 ERA

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Astros vs. Royals Odds [4/26/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Astros vs. Royals Picks and Best Bets

Our model's biggest edge in today's Astros vs. Royals matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

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Astros vs. Royals Game-Day Updates and Essential Details

Saturday's MLB matchup between the Royals and Astros at Kauffman Stadium is scheduled to start at 7:10PM ET.

• Who: Houston Astros vs. Kansas City Royals
• Date: Saturday, April 26, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Kauffman Stadium

Dimers.com's in-depth preview of Saturday's Astros vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any Houston vs. Kansas City picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Astros, with a 56% win probability, will likely beat the Royals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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