Astros vs. Guardians Prediction: Guardians Predicted to Win Following Latest Data Analysis for Friday's MLB Game [9/27/2024]

The Cleveland Guardians will face the Houston Astros in MLB action at Progressive Field on Friday, commencing at 7:10PM ET.

The Guardians will send Joey Cantillo (2-3, 4.63 ERA) to the mound, while the Astros are going with Ronel Blanco (12-6, 2.88 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Guardians as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Astros-Guardians game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Guardians' chance of winning is 54% , while the Astros' is 46%."

Astros vs. Guardians Game-Day Updates and Essential Details

Friday's MLB game between the Guardians and Astros at Progressive Field is scheduled to commence at 7:10PM ET.

• Who: Houston Astros vs. Cleveland Guardians
• Date: Friday, September 27, 2024
• Time: 7:10PM ET/4:10PM PT
• Venue: Progressive Field
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Guardians and Astros gear at Fanatics
• Live Stream: Watch the game on FuboTV

Dimers.com's full preview of Friday's Astros vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Guardians vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Astros vs. Guardians Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Friday's MLB matchup between the Astros and Guardians 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Guardians a 54% chance of defeating the Astros.

According to our model, the Guardians (+1.5) have a 65% chance of covering the run line, while the 8.5-run over/under has a 55% chance of going over.

Astros vs. Guardians Odds [9/27/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Astros	Guardians
Run Line	-1.5 (+165)	+1.5 (-194)
Moneyline	+105	-120
Total	o8.5 (-105)	u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

Astros vs. Guardians Picks

Our model's biggest edge in today's Astros vs. Guardians matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks for every game throughout the season.

Full access to our picks, including this one, is available via Dimers Pro.

Calling Our Shot: Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Conclusion

We predict the Guardians, with a 54% win probability, will likely beat the Astros on Friday.

AI and automation have enhanced this article to quickly deliver accurate Astros vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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