Holy Cross vs. Buffalo CFB Prediction and Odds - Sep 10, 2022

Buffalo squares off with Holy Cross in College Football action at UB Stadium on Saturday, with kickoff at 6:00PM ET.

Dimers' free betting picks for Holy Cross vs. Buffalo, plus game predictions and best odds, are featured below.

Today's Holy Cross vs. Buffalo betting analysis is brought to you by DraftKings Sportsbook, which has a tasty Bet $5, Win $200 promo for new customers.

Who will win Holy Cross vs. Buffalo?

Based on trusted computer power and data, Dimers.com has simulated Holy Cross vs. Buffalo 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives Buffalo a 65% chance of winning against Holy Cross.

More: Free Betting Analysis for Holy Cross vs. Buffalo

Holy Cross vs. Buffalo Game Odds

• Spread: Buffalo -6.5 (-118), Holy Cross +6.5 (-102)
• Moneyline: Buffalo -230, Holy Cross +202
• Total: Over/Under 51.5 (-110/-105)

Point Spread, Moneyline and Over/Under

Buffalo is currently the -6.5 favorite against Holy Cross, with -118 at FanDuel Sportsbook the best odds currently available.

For the underdog Holy Cross (+6.5) to cover the spread, FanDuel Sportsbook also has the best odds currently on the market at -102.

DraftKings Sportsbook currently has the best moneyline odds for Buffalo at -230, which means you can risk $230 to win $100, for a total payout of $330, if it gets the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for Holy Cross at +202, where you can bet $100 to profit $202, earning a total payout of $302, if it wins.

The Over/Under sits at 51.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Holy Cross (+6.5) is a 52% chance of covering the spread, while the Over/Under total of 51.5 points is a 53% chance of going Under.

More: Predictions for Every CFB Game

Best Bets for Holy Cross vs. Buffalo

• Spread: Holy Cross +6.5 @ -102 via FanDuel Sportsbook (52% probability)
• Moneyline: Holy Cross @ +202 via FanDuel Sportsbook (2.1% edge)
• Total: Under 51.5 @ -105 via FanDuel Sportsbook (53% probability)

Our best bets are based on complex modeling and gambling expertise to bring you the best possible plays every time.

While Buffalo is more likely to win the game, according to DimersBOT, taking Holy Cross moneyline is the best option due to the 2.1% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being a profitable bettor in the long run.

Holy Cross vs. Buffalo Prediction

Dimers.com's predicted final score for Holy Cross vs. Buffalo at UB Stadium this Saturday has Buffalo winning 27-22.

Click or tap on See Matchup to reveal more.

Dimers has full coverage of this week's Holy Cross-Buffalo matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so refresh this page for any changes to our betting insights before Holy Cross vs. Buffalo on Saturday September 10, 2022.

Holy Cross vs. Buffalo 2022 CFB Game Info

Saturday's action between Buffalo and Holy Cross in College Football at UB Stadium is scheduled to start at 6:00PM ET.

• Who: Holy Cross vs. Buffalo
• Date: Saturday September 10, 2022
• Time: 6:00PM ET / 3:00PM PT
• Venue: UB Stadium

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