Guardians vs. White Sox Prediction and Odds - May 16, 2023

The Chicago White Sox and Cleveland Guardians meet in MLB action at Guaranteed Rate Field on Tuesday, starting at 8:10PM ET.

Lance Lynn (1-5, 7.51 ERA) will start on the mound for the White Sox, up against Shane Bieber (3-1, 2.61 ERA) for the Guardians.

Dimers' best betting picks for Guardians vs. White Sox, as well as game predictions and betting odds, are detailed below.

Who Will Win: Guardians vs. White Sox

Using advanced computer power and data, Dimers.com has simulated Tuesday's Guardians-White Sox MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, can't split the two teams, giving both the Guardians and White Sox a 50% chance of winning the game.

More: Guardians vs. White Sox Simulated 10K Times

Guardians vs. White Sox Odds

• Run Line: White Sox +1.5 (-160), Guardians -1.5 (+140)
• Moneyline: White Sox +105, Guardians -120
• Total: Over/Under 8.5 (-108/-110)

Run Line, Moneyline and Over/Under

The White Sox are +1.5 underdogs versus the Guardians, with -160 at PointsBet the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +140.

PointsBet currently has the best moneyline odds for the White Sox at +105. That means you can bet $100 to profit $105, earning a total payout of $205, if they win.

Meanwhile, BetMGM currently has the best moneyline odds for the Guardians at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under for total runs scored is set at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -108, while PointsBet currently has the best odds for the Under at -110.

As always, make sure you check all of the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) have a 63% chance of covering the run line, while the 8.5-run Over/Under has a 51% chance of going Under.

More: Predictions for Every MLB Matchup

Best Bets for Guardians vs. White Sox

• Run Line: White Sox +1.5 @ -160 via PointsBet (63% probability)
• Moneyline: White Sox @ +105 via PointsBet (50% probability)
• Total: Under 8.5 @ -110 via PointsBet (51% probability)

Dimers' best bets are based on detailed simulations and wagering expertise to serve you the best possible plays 24/7.

Guardians vs. White Sox Prediction

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Dimers has full coverage of Tuesday's Guardians-White Sox matchup, including pregame predictions, computer picks, and live scores.

Don't forget, DimersBOT updates often, so check this page for the latest betting insights before Guardians vs. White Sox on Tuesday May 16, 2023.

Guardians vs. White Sox 2023

Tuesday's game between the White Sox and Guardians at Guaranteed Rate Field is scheduled to start at 8:10PM ET.

• Who: Cleveland Guardians vs. Chicago White Sox
• Date: Tuesday May 16, 2023
• Time: 8:10PM ET / 5:10PM PT
• Venue: Guaranteed Rate Field

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Make Smarter Sports Betting Decisions with Dimers

Dimers' predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Guardians vs. White Sox picks can help you make informed decisions, it's important that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What MLB Games Are on Today?

The Guardians and White Sox aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every MLB game via our MLB Predictions page.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

In addition to MLB picks and predictions, we also provide the best MLB prop bets for today, projecting home runs, RBIs, and more against the best odds available every day of the MLB season.

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities compared to the best odds available.