Guardians vs. Twins Prediction and Odds - Sep 10, 2022

The Minnesota Twins take on the Cleveland Guardians in MLB action at Target Field on Saturday, starting at 7:15PM ET.

The Twins will have Chris Archer (2-7, 4.47 ERA) start, while the Guardians will counter with Triston McKenzie (9-11, 3.18 ERA).

Dimers' top betting picks for Guardians vs. Twins, plus game predictions and betting odds, are featured below.

Who will win Guardians vs. Twins?

Based on high-tech computer power and data, Dimers.com has simulated Saturday's Guardians-Twins MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Guardians a 52% chance of beating the Twins.

More: Guardians vs. Twins Simulated 10,000 Times

Guardians vs. Twins Game Odds

• Run Line: Twins +1.5 (-164), Guardians -1.5 (+142)
• Moneyline: Twins +100, Guardians -116
• Total: Over/Under 7.5 (-105/-114)

Run Line, Moneyline and Over/Under

The Twins are currently +1.5 underdogs versus the Guardians, with -164 at Caesars Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +142.

BetMGM currently has the best moneyline odds for the Twins at +100. That means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Guardians at -116, where you can risk $116 to win $100, for a total payout of $216, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with BetMGM, which currently has the best odds for the Over at -105, while FanDuel Sportsbook currently has the best odds for the Under at -114.

As always, check out all of the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Twins (+1.5) are a 61% chance of covering the run line, while the 7.5-run Over/Under is a 52% chance of going Over.

More: Best Prop Bets to Make Today

Best Bets for Guardians vs. Twins

• Run Line: Twins +1.5 @ -164 via Caesars Sportsbook (61% probability)
• Moneyline: Guardians @ -116 via FanDuel Sportsbook (52% probability)
• Total: Over 7.5 @ -105 via BetMGM (52% probability)

Dimers' best bets are based on detailed simulations and gambling expertise to serve you the best possible plays 24/7.

Guardians vs. Twins Probabilities

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Dimers has full coverage of Saturday's Guardians-Twins matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this page for the latest betting insights ahead of Guardians vs. Twins on Saturday September 10, 2022.

Guardians vs. Twins 2022 Game Info

Saturday's game between the Twins and Guardians at Target Field is scheduled to start at 7:15PM ET.

• Who: Cleveland Guardians vs. Minnesota Twins
• Date: Saturday September 10, 2022
• Time: 7:15PM ET / 4:15PM PT
• Venue: Target Field

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