Guardians vs. Royals Prediction and Odds - Sep 6, 2022

MLB action continues on Tuesday at 8:10PM ET as the Cleveland Guardians lock horns with the Kansas City Royals at Kauffman Stadium.

The Royals will have Kris Bubic (2-10, 5.47 ERA) start, while the Guardians will counter with Shane Bieber (8-8, 3.06 ERA).

Dimers' top betting picks for Guardians vs. Royals, plus game predictions and betting odds, are featured below.

Who will win Guardians vs. Royals?

Based on high-tech machine learning and data, Dimers.com has simulated Tuesday's Guardians-Royals MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Guardians a 60% chance of defeating the Royals.

More: Guardians vs. Royals Simulated 10K Times

Guardians vs. Royals Game Odds

• Run Line: Royals +1.5 (+100), Guardians -1.5 (-115)
• Moneyline: Royals +176, Guardians -200
• Total: Over/Under 7.5 (+100/-112)

Run Line, Moneyline and Over/Under

The Royals are listed as +1.5 underdogs against the Guardians, with +100 at DraftKings Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -115.

FanDuel Sportsbook currently has the best moneyline odds for the Royals at +176, which means you can bet $100 to profit $176, earning a total payout of $276, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Guardians at -200, where you can risk $200 to win $100, for a total payout of $300, if they come out on top.

The Over/Under sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -112.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 55% chance of covering the run line, while the 7.5-run Over/Under is a 51% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Guardians vs. Royals

• Run Line: Royals +1.5 @ +100 via DraftKings Sportsbook (55% probability) 🔥
• Moneyline: Royals @ +176 via FanDuel Sportsbook (3.7% edge)
• Total: Over 7.5 @ +100 via Caesars Sportsbook (51% probability)

If you see a 🔥, you know you've found one of our best free picks today across all major pro and college sports.

Our best bets are based on complex simulations and gambling expertise to serve you the best possible plays every day of the year.

While the Guardians are more likely to win the game, according to DimersBOT, taking the Royals moneyline is the best option due to the 3.7% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers.com is crucial to achieving long-term profitability.

Guardians vs. Royals Prediction

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Dimers has full coverage of Tuesday's Guardians-Royals matchup, including pregame predictions, computer picks, and live scores.

Remember, DimersBOT updates regularly, so check this article for the latest betting analysis before Guardians vs. Royals on Tuesday September 6, 2022.

Guardians vs. Royals 2022 Game Info

Tuesday's game between the Royals and Guardians at Kauffman Stadium is scheduled to start at 8:10PM ET.

• Who: Cleveland Guardians vs. Kansas City Royals
• Date: Tuesday September 6, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Kauffman Stadium

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What MLB games are on today?

Now you've got the 411 on Guardians vs. Royals, take a look at the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.