Guardians vs. Rangers Prediction and Odds - Sep 25, 2022

The Texas Rangers and Cleveland Guardians clash in MLB at Globe Life Field on Sunday, starting at 2:35PM ET.

Cole Ragans (0-2, 5.40 ERA) will start on the mound for the Rangers, while the Guardians will counter with Aaron Civale (2-6, 5.29 ERA).

Dimers' top betting picks for Guardians vs. Rangers, as well as game predictions and best odds, are featured in this article.

Who will win Guardians vs. Rangers?

Using advanced computer power and data, Dimers.com has simulated Sunday's Guardians-Rangers MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Guardians a 53% chance of defeating the Rangers.

More: Guardians vs. Rangers Simulated 10K Times

Guardians vs. Rangers Game Odds

• Run Line: Rangers +1.5 (-145), Guardians -1.5 (+126)
• Moneyline: Rangers +112, Guardians -130
• Total: Over/Under 8 (-115/+100)

Run Line, Moneyline and Over/Under

The Rangers are +1.5 underdogs versus the Guardians, with -145 at Caesars Sportsbook the best odds currently available.

For the favored Guardians (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +126.

FanDuel Sportsbook currently has the best moneyline odds for the Rangers at +112. That means you can bet $100 to profit $112, earning a total payout of $212, if they win.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Guardians at -130, where you can risk $130 to win $100, for a total payout of $230, if they come out on top.

The Over/Under for total runs scored is set at 8 with BetMGM, which currently has the best odds for the Over at -115, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Rangers (+1.5) are a 60% chance of covering the run line, while the Over/Under total of 8 runs is a 56% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Guardians vs. Rangers

• Run Line: Rangers +1.5 @ -145 via Caesars Sportsbook (60% probability)
• Moneyline: Rangers @ +112 via FanDuel Sportsbook (0.3% edge)
• Total: Over 8 @ -115 via BetMGM (56% probability)

Dimers' best bets are based on detailed simulations and betting expertise to help you make smarter decisions with your state's legal sportsbooks.

While the Guardians are more likely to win the game, according to DimersBOT, betting on the Rangers moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is one of the keys to being profitable in the long run.

Guardians vs. Rangers Betting Guide

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Dimers has full coverage of Sunday's Guardians-Rangers matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this article for the latest betting analysis before Guardians vs. Rangers on Sunday September 25, 2022.

Guardians vs. Rangers 2022 Game Info

Sunday's matchup between the Rangers and Guardians at Globe Life Field is scheduled to begin at 2:35PM ET.

• Who: Cleveland Guardians vs. Texas Rangers
• Date: Sunday September 25, 2022
• Time: 2:35PM ET / 11:35AM PT
• Venue: Globe Life Field

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What other MLB games are on today?

Now you've got the 411 on Guardians vs. Rangers, check out the latest betting analysis for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.