Guardians vs. Padres Prediction and Odds - Aug 23, 2022

The San Diego Padres square off with the Cleveland Guardians in MLB action at PETCO Park on Tuesday, commencing at 9:40PM ET.

The Padres will have Mike Clevinger (4-4, 3.63 ERA) start, while the Guardians are going with Aaron Civale (2-5, 5.62 ERA).

Dimers' top betting picks for Guardians vs. Padres, as well as game predictions and best odds, are detailed below.

Who will win Guardians vs. Padres?

Using state-of-the-art computer power and data, Dimers.com has simulated Tuesday's Guardians-Padres MLB matchup 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, currently gives the Padres a 58% chance of defeating the Guardians.

More: Guardians vs. Padres Simulated 10,000 Times

Guardians vs. Padres Game Odds

• Run Line: Padres -1.5 (+145), Guardians +1.5 (-164)
• Moneyline: Padres -140, Guardians +130
• Total: Over/Under 7.5 (-115/+100)

Run Line, Moneyline and Over/Under

The Padres are currently -1.5 favorites versus the Guardians, with +145 at DraftKings Sportsbook the best odds currently available.

For the underdog Guardians (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -164.

DraftKings Sportsbook currently has the best moneyline odds for the Padres at -140, which means you can risk $140 to win $100, for a total payout of $240, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Guardians at +130, where you can bet $100 to profit $130, earning a total payout of $230, if they win.

The Over/Under is set at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 62% chance of covering the run line, while the Over/Under total of 7.5 runs is a 55% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Guardians vs. Padres

• Run Line: Guardians +1.5 @ -164 via Caesars Sportsbook (62% probability)
• Moneyline: Padres @ -140 via DraftKings Sportsbook (58% probability)
• Total: Over 7.5 @ -115 via FanDuel Sportsbook (55% probability)

Our best bets are based on detailed simulations and wagering expertise to bring you the best possible plays every day of the year.

Guardians vs. Padres Prediction

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cleveland vs. San Diego, and click or tap on See Matchup for more.

Dimers has full betting coverage of Tuesday's Guardians-Padres matchup, including pregame predictions, best betting picks, and live updates.

Remember, DimersBOT updates regularly, so keep an eye on this page for the latest betting insights before Guardians vs. Padres on Tuesday August 23, 2022.

Best Sportsbook Offer for Guardians vs. Padres

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Guardians vs. Padres 2022 Game Info

Tuesday's action between the Padres and Guardians at PETCO Park is scheduled to commence at 9:40PM ET.

• Who: San Diego Padres vs. Cleveland Guardians
• Date: Tuesday August 23, 2022
• Time: 9:40PM ET / 6:40PM PT
• Venue: PETCO Park

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