Giants vs. Padres Prediction and Odds - Oct 5, 2022

The San Diego Padres and San Francisco Giants are scheduled to meet in MLB at PETCO Park on Wednesday, starting at 4:10PM ET.

The Padres will send Craig Stammen (1-1, 3.58 ERA) to the mound, pitting him against John Brebbia (6-2, 3.09 ERA) for the Giants.

Dimers' top betting picks for Giants vs. Padres, as well as game predictions and best odds, are detailed in this article.

Who will win Giants vs. Padres?

Using high-tech computer power and data, Dimers.com has simulated Wednesday's Giants-Padres MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Padres a 56% chance of defeating the Giants.

More: Giants vs. Padres Simulated 10,000 Times

Giants vs. Padres Current Odds

• Run Line: Padres -1.5 (+155), Giants +1.5 (-170)
• Moneyline: Padres -130, Giants +120
• Total: Over/Under 8 (-115/+105)

Run Line, Moneyline and Over/Under

The Padres are currently -1.5 favorites against the Giants, with +155 at BetMGM the best odds currently available.

For the underdog Giants (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -170.

BetMGM currently has the best moneyline odds for the Padres at -130, which means you can risk $130 to win $100, for a total payout of $230, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Giants at +120, where you can bet $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under for total runs scored is set at 8 with BetMGM, which currently has the best odds for the Over at -115, while Caesars Sportsbook currently has the best odds for the Under at +105.

As always, make sure you check all of the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Giants (+1.5) are a 62% chance of covering the run line, while the Over/Under total of 8 runs is a 59% chance of going Over.

More: Track Your Bets via Bet Center

Best Bets for Giants vs. Padres

• Run Line: Padres -1.5 @ +155 via BetMGM
• Moneyline: Padres @ -130 via BetMGM (56% probability)
• Total: Over 8 @ -115 via BetMGM (59% probability) 🔥

Every time you see a 🔥, that means you've found one of our best bets today across all sports.

Dimers' best bets are based on complex simulations and gambling intelligence to serve you the best possible plays 24/7.

Although the Giants are more likely to cover the run line, our best bet of Padres -1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

Giants vs. Padres Prediction

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Dimers has full coverage of Wednesday's Giants-Padres matchup, including pregame predictions, free betting picks, and live scores.

Don't forget, DimersBOT updates frequently, so keep checking this page for the latest betting analysis ahead of Giants vs. Padres on Wednesday October 5, 2022.

Giants vs. Padres 2022 Game Info

Wednesday's matchup between the Padres and Giants at PETCO Park is scheduled to start at 4:10PM ET.

• Who: San Francisco Giants vs. San Diego Padres
• Date: Wednesday October 5, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: PETCO Park

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