Giants vs. Diamondbacks Prediction and Odds - Jul 27, 2022

The Arizona Diamondbacks take on the San Francisco Giants in MLB action at Chase Field on Wednesday, commencing at 3:40PM ET.

The Diamondbacks will send Zac Gallen (5-2, 3.31 ERA) to the mound, up against Logan Webb (9-3, 2.76 ERA) for the Giants.

Dimers' free betting picks for Giants vs. Diamondbacks, as well as game predictions and best odds, are featured below.

Who will win Giants vs. Diamondbacks?

Based on advanced computer power and data, Dimers.com has simulated Wednesday's Giants-Diamondbacks MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, can't split the two teams, giving both the Giants and Diamondbacks a 50% chance of winning the game.

More: Full Betting Guide for Giants vs. Diamondbacks

Giants vs. Diamondbacks Game Odds

• Run Line: Diamondbacks +1.5 (-169), Giants -1.5 (+150)
• Moneyline: Diamondbacks -104, Giants -112
• Total: Over/Under 7.5 (-115/-105)

Run Line, Moneyline and Over/Under

The Diamondbacks are +1.5 underdogs versus the Giants, with -169 at Caesars Sportsbook the best odds currently available.

For the favored Giants (-1.5) to cover the run line, PointsBet has the best odds currently on offer at +150.

In a sign of how close this game is expected to be, both the Diamondbacks and Giants are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Diamondbacks at -104, which means you can risk $104 to win $100, for a total payout of $204, if they get the W.

Meanwhile, FanDuel Sportsbook also has the best moneyline odds for the Giants at -112, where you can risk $112 to win $100, for a total payout of $212, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -115, while BetMGM currently has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 63% chance of covering the run line, while the 7.5-run Over/Under is a 54% chance of going Over.

More: Track Your Bets via Dimers' Bet Center

Best Bets for Giants vs. Diamondbacks

• Run Line: Diamondbacks +1.5 @ -169 via Caesars Sportsbook (63% probability)
• Moneyline: Diamondbacks @ -104 via FanDuel Sportsbook (50% probability)
• Total: Over 7.5 @ -115 via Caesars Sportsbook (54% probability)

Our best bets are based on detailed simulations and gambling intelligence to help you make more informed investments with your state's legal sportsbooks.

Giants vs. Diamondbacks Prediction

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for San Francisco vs. Arizona, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Giants-Diamondbacks matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this article for any changes to our betting insights ahead of Giants vs. Diamondbacks on Wednesday July 27, 2022.

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Giants vs. Diamondbacks 2022 Game Info

Wednesday's game between the Diamondbacks and Giants at Chase Field is scheduled to commence at 3:40PM ET.

• Who: Arizona Diamondbacks vs. San Francisco Giants
• Date: Wednesday July 27, 2022
• Time: 3:40PM ET / 12:40PM PT
• Venue: Chase Field

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Want more MLB analysis like this?

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We use the power of predictive analytics to find edges in the markets so we can produce the most comprehensive MLB betting previews out there. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.