Giants vs. Cubs Prediction and Odds - Sep 10, 2022

MLB action continues on Saturday at 2:20PM ET as the San Francisco Giants take on the Chicago Cubs at Wrigley Field.

The Cubs will send Marcus Stroman (3-6, 3.73 ERA) to the mound, pitting him against Logan Webb (12-8, 2.90 ERA) for the Giants.

Dimers' top betting picks for Giants vs. Cubs, as well as game predictions and best odds, are featured below.

Who will win Giants vs. Cubs?

Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's Giants-Cubs MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Giants a 51% chance of beating the Cubs.

More: Giants vs. Cubs Simulated 10K Times

Giants vs. Cubs Odds

• Run Line: Cubs +1.5 (-164), Giants -1.5 (+150)
• Moneyline: Cubs +102, Giants -115
• Total: Over/Under 7.5 (-110/-106)

Run Line, Moneyline and Over/Under

The Cubs are listed as +1.5 underdogs against the Giants, with -164 at Caesars Sportsbook the best odds currently available.

For the favored Giants (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +150.

FanDuel Sportsbook currently has the best moneyline odds for the Cubs at +102, which means you can throw down $100 to profit $102, earning a total payout of $202, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Giants at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 62% chance of covering the run line, while the 7.5-run Over/Under is a 52% chance of going Over.

More: Free Prop Picks

Best Bets for Giants vs. Cubs

• Run Line: Cubs +1.5 @ -164 via Caesars Sportsbook (62% probability)
• Moneyline: Cubs @ +102 via FanDuel Sportsbook
• Total: Over 7.5 @ -110 via Caesars Sportsbook (52% probability)

Our best bets are based on detailed modeling and wagering expertise to bring you the best possible plays every time.

While the Giants are more likely to win the game, according to DimersBOT, betting on the Cubs moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers.com is pivotal to achieving long-term profitability as a bettor.

Giants vs. Cubs Probabilities

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Dimers has full betting coverage of Saturday's Giants-Cubs matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep checking this article for the latest betting analysis ahead of Giants vs. Cubs on Saturday September 10, 2022.

Giants vs. Cubs 2022 Game Info

Saturday's matchup between the Cubs and Giants at Wrigley Field is scheduled to commence at 2:20PM ET.

• Who: San Francisco Giants vs. Chicago Cubs
• Date: Saturday September 10, 2022
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

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What other MLB games are on today?

Now you've got the 411 on Giants vs. Cubs, see the latest betting analysis for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.