Florida vs. South Carolina CFB Predictions and Odds - Nov 6, 2021

South Carolina hosts the favored Florida in College Football Week 10 action at Williams-Brice Stadium on Saturday, beginning at 7:30 PM EDT.

Dimers' free betting picks for Florida vs. South Carolina, as well as our score prediction and best odds, are featured in this article.

Who will win Florida vs. South Carolina?

Based on high-tech machine learning and data, Dimers.com has simulated Saturday's Florida-South Carolina matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives Florida a 90% chance of defeating South Carolina.

MORE: Florida vs. South Carolina simulated 10,000 times

Florida vs. South Carolina Point Spread, Moneyline and Over/Under

South Carolina is the +21.5 underdog at home to Florida, with -118 at FanDuel Sportsbook the best odds available.

For the favored Florida (-21.5) to cover the spread, FanDuel Sportsbook also has the best odds on offer at -104.

FanDuel Sportsbook has the best moneyline odds for South Carolina at +820. That means you can bet $100 to profit $820, earning a total payout of $920, if it wins.

On the other hand, DraftKings Sportsbook has the best moneyline odds for Florida at -1250, where you can risk $1250 to win $100, for a total payout of $1350, if it comes out on top.

The Over/Under sits at 52.5 with FanDuel Sportsbook, which has the best odds for the Over at -112, as well as the best odds for the Under at -108.

As always, make sure you check the sportsbooks you can bet with in your state for the best College Football odds and lines.

According to DimersBOT, South Carolina (+21.5) is a 53% chance of covering the spread, while the Over/Under total of 52.5 points is a 55% chance of going Under.

Best Bets for Florida vs. South Carolina

• Spread: South Carolina +21.5 at -118 with FanDuel Sportsbook (53% probability)
• Moneyline: South Carolina Win at +820 with FanDuel Sportsbook
• Over/Under: Under 52.5 at -108 with FanDuel Sportsbook (55% probability)

While Florida is more likely to win the game, according to DimersBOT, betting on South Carolina moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges published on Dimers is crucial to being a profitable bettor in the long run.

MORE: Best bets today for all major US and international sports

Florida vs. South Carolina Predicted Score

Dimers.com's predicted score for Florida vs. South Carolina at Williams-Brice Stadium on Saturday has Florida winning 36-16.

Dimers has full betting coverage of this week's Florida-South Carolina matchup, including pre-game predictions, free picks, live win probabilities, and play-by-play commentary.

Remember, DimersBOT updates often, so check this article for the latest ahead of Florida vs. South Carolina on Saturday November 6, 2021.

Florida vs. South Carolina 2021 CFB Game Info

When does South Carolina play Florida?

• Date: Saturday November 6, 2021
• Time: 7:30 PM EDT / 4:30 PM PDT
• Venue: Williams-Brice Stadium

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We use the power of predictive analytics to find edges in the markets so we can produce the best CFB betting previews available. We're able to do this by comparing our accurate and powerful probabilities against the sportsbooks' odds as soon as they go live.

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