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March Madness Parlay, Picks & Odds for NCAA Final Four on Saturday, April 5

The 2025 March Madness NCAAB Tournament has reached its final stretch with Saturday's Final Four games, Florida vs. Auburn and Duke vs. Houston, determining who will play in the National Championship game on Monday, April 7.
This has been our biggest college basketball season yet - from Dimers Pro to our Dimers Brackets and our brand-new college basketball player prop projections hub, we came into this tournament ready to dominate, and we did that, with an elite 76% hit rate on our first round bets, yielding a profit of over 11 units on straight bets over just two days.
With just three games left in the tournament, we're going to feature our best bet and prop from each game, plus who to play them together for a +1062 college basketball parlay.
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Best Bets, Props and Parlay Picks for Florida-Auburn and Duke-Houston
After simulating each game over 10,000 times, our model has identified the following bets and props as our top picks in Florida vs. Auburn and Duke vs. Houston.
Note, if you don't have these bets available due to state restrictions, you can view our other college basketball best bets or consider using the Dimers Pro Parlay Picker to craft a two-leg parlay for Saturday's games.
#1 Florida vs. #1 Auburn
Best Bet: Under 159.5 Points (-110 on bet365)
Our top edge in Florida vs. Auburn is on the game total, with our model predicting the under which is set at 159.5 points at a 53.8% probability, giving us an edge over 2%.
With a final score prediction of 79-76 in favor of Florida, we project 153 total points, going under by 6.5 points on average.
So far in the tournament, Florida has gone over in all four games by a total of +4.4 points while Auburn has gone under their game totals three times, for differential of -5.9 points. Florida has the 23rd-ranked defense by efficiency this season while Auburn ranks 35th so this could be more of a defensive battle than a high-scoring game as suggested by the total.
It's no surprise to see this game with the much higher total compared to Duke-Houston, however given our model's probability and value, the Under looks like the play.
Best Prop: Johni Broome Under 10.5 Rebounds (-125 on bet365)
Out of all the value props in this game, our highest probability is on Auburn star Johni Broome to go under his rebounds total of 10.5.
At a 65.4% probability, this is our most likely prop in this game and it comes with a 12.1% edge as our model says the odds should be closer to -190, with a projection of 8.3 rebounds for Broome.
He's been productive at grabbing boards in the tournament, but he gets more off of defensive rebounds and Florida is a strong shooting team and ranks 4th in offensive rebounds per game, 7thin defensive rebounds and they've only allowed one player to grab more than rebounds through four games of the tournament.
#1 Duke vs. #1 Houston
Best Bet: Over 136.5 Points (-110 on bet365)
In this game, our model is predicting the Over with an even higher 56.1% probability of the game going over 136.5 total points. At odds of -110, that gives us a valuable edge of 3.7%, suggesting these odds should be closer to -130.
We predict a final score of 74-68 in favor of Duke, going over the total by 5.5 points (142 on average).
Duke has a 3-1 record to the over in the tournament so far with a +5.9 point differential, while Houston has the opposite record, and a -3.5 point differential. Though these teams have two of the top-ranked defenses, Duke has scored 85+ points in every tournament game and our model predicts both teams to have success shooting the ball.
Best Prop: L.J. Cryer Over 2.3 Three Pointers (-105 on bet365)
In the second game of the night, our model's top prop is on Houston Cougars guard L.J. Cryer to knock down over 2.5 three-pointers, a mark he's hit in 2/4 tournament games.
The DimersBOT gives Cryer a 67.0% probability to go knock down at least a trio of threes, projecting him for 3.8 with an edge of 13.8% against his odds of -105.
Cryer, a 41.9% three-point shooter this season, is under in two straight, but had strong volume in his last game, putting up 8 threes and hitting a pair. Duke presents a stout defense but have allowed an opposing player to hit this mark in each game of the tournament.
Semifinals Parlay odds: +1062 (Bet $10 to Win $106.20)
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To unlock this bonus code and earn $150 in bonus bets on today's college basketball parlay picks, new users simply need to register with Bet365, enter the bonus code DIMERS during sign-up, and place a qualifying wager of $5 or more on today's parlay. Upon doing so, $150 in bonus bets will be credited instantly.
Dimers' 2025 March Madness Betting Resources
- CBB Predictions: Our data-backed previews for every game, every day
- CBB Best Bets: Our Top Picks for every individual matchup
- Best CBB Props: Player edges and projections from our predictive analytics model
- CBB Futures Odds: Who will win the 2025 March Madness Tournament?
- CBB Betting News: The latest promos, storylines and more around the league
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