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Experts Update Bears vs. 49ers Prediction Following Reports that D'Andre Swift and DJ Moore WILL Play in Week 14, Bosa and Willams OUT

The Chicago Bears will take on the San Francisco 49ers in Week 14 of the NFL season at Levi's Stadium on Sunday. Kickoff is at 4:25 p.m. EST.
All week, questions have lingered over the availability of Bears running back D'Andre Swift and wide receiver DJ Moore, both of whom were listed as questionable on Chicago's final Week 14 injury report.
With kickoff just a few hours away, NFL Network's Ian Rapoport has reported that both Swift and Moore are expected to play against the 49ers in NFL Week 14, according to to Chicago interim head coach Thomas Brown.
Meanwhile, the 49ers have scratched all-pros Nick Bosa and Trent Williams once again.
Having lost first and second string running backs Christian McCaffrey and Jordan Mason to the injured reserve last week, San Francisco elevated RB Patrick Taylor from the practice squad. Former third-stringer Isaac Guerendo will lead the 49ers' backfield on Week 14 Sunday.
In light of these updates, our data analysts conducted 10,000 simulations of the Bears-49ers matchup early Sunday morning, taking into account each team's latest roster developments. The results were compared to current NFL betting odds to inform the data-driven Bears vs 49ers betting guide below.
Bears vs. 49ers betting preview
This preview includes our best bets and predicted scoreline for the Chicago Bears Lions vs. San Francisco 49ers. To access our full suite of advanced NFL betting data free for three months, join BetMGM with code "DIMERSPRO". This will also unlock BetMGM's $1,500 first bet offer, which can be used alongside Bet365's $150 bonus bet offer, and is valid for the Bears vs. 49ers and all other NFL Week 14 games.
Game details
The key information you need before the Bears vs. 49ers NFL game.
- Teams: Chicago Bears vs. San Francisco 49ers
- Date: Sunday, December 8, 2024
- Kickoff: 4:25 p.m. EST
- Location: Levi's Stadium
- Projected boxscore: Check our projected player stats for the Bears vs. 49ers
- NFL standings: Current NFL division standings
- NFL injuries: Check the latest updates to the official NFL injury report
Odds
The latest and best odds for the NFL battle between the Bears and 49ers.
- Spread: Bears +3.5 (-120), 49ers -3.5 (-102)
- Moneyline: Bears +145, 49ers -170
- Total: Over/Under 44.5 (-105/-115)
The odds and lines presented in this article are the best available from selected sports betting sites at the time of publication and are subject to change.
Expert prediction: Bears vs. 49ers
Using cutting-edge data analysis and computer power, our experts have performed 10,000 simulations of Sunday's Bears vs. 49ers game.
According to our predictive analytics model, the 49ers are more likely to defeat the Bears at Levi's Stadium. This prediction is based on the model giving the 49ers a 61% chance of winning the game.
Furthermore, we predicts that the Bears (+3.5) have a 56% chance of covering the spread, while the over/under total of 44.5 points has a 54% chance of staying under.
As always, these predictions and probabilities are accurate at the time of publication but are subject to change.
Bears vs. 49ers best bet
Our top pick for the Bears vs. 49ers Week 14 NFL game is to bet on the Bears +3.5 (-120).
This expert betting advice is formulated through world-class modeling and valuable wagering intelligence, designed to bring you the best possible plays.
Score prediction for Bears vs. 49ers
Our projected final score for the Chicago vs. San Francisco game on Sunday has the 49ers winning 23-20.
This expert prediction is based on each team's average score following 10,000 game simulations, offering a glimpse into the potential outcome.
NFL player props: Sunday
NFL prop picks are an exciting way to wager on Sunday's game without necessarily betting on its outcome.
This article features the most likely first and anytime touchdown scorers for the Bears and 49ers, along with projected player stats.
Chicago Bears
First touchdown scorer predictions
- D'Andre Swift: 8.8% probability
- DJ Moore: 8.5% probability
- Rome Odunze: 7.1% probability
Anytime touchdown predictions
- D'Andre Swift: 37.7% probability
- DJ Moore: 36.3% probability
- Rome Odunze: 31.3% probability
Projected box score leaders
- QB passing yards: Caleb Williams, 203 yards
- Receiving yards: DJ Moore, 72 yards
- Rushing yards: D'Andre Swift, 59 yards
San Francisco 49ers
First touchdown scorer predictions
- Isaac Guerendo: 12.3% probability
- George Kittle: 9.2% probability
- Deebo Samuel: 8.6% probability
Anytime touchdown predictions
- Isaac Guerendo: 48.7% probability
- George Kittle: 38.1% probability
- Deebo Samuel: 36.3% probability
Projected box score leaders
- QB passing yards: Brock Purdy, 257 yards
- Receiving yards: Jauan Jennings, 59 yards
- Rushing yards: Isaac Guerendo, 76 yards
NFL Week 14: Bears vs. 49ers
Get ready for Sunday's game between the Bears and 49ers in Week 14 of the National Football League season at Levi's Stadium, which is scheduled to start at 4:25 p.m. EST. We emphasize that all of the NFL best bets and NFL predictions in this preview are based on 10,000 data-driven simulations of the Bears vs. 49ers game, and they are correct at the time of publishing to help you make better decisions when placing bets at online sportsbooks.
Please note that when engaging in online betting, it is important to exercise responsible gambling practices and consult trustworthy sources for accurate and up-to-date information.