Duke vs. Louisville CFB Prediction and Odds - October 28, 2023

Louisville and Duke meet in College Football action at L&N Federal Credit Union Stadium on Saturday, with kickoff at 3:30PM ET.

Dimers' prediction for Saturday's Duke vs. Louisville game, plus the latest odds and our full game preview, are detailed below.

Today's Duke vs. Louisville prediction is sponsored by Bet365, which has a Bet $5, Get $150 in Bonus Bets promo for new users.

Who Will Win: Duke vs. Louisville

Based on trusted machine learning and data, Dimers.com has simulated the outcome of Duke vs. Louisville 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives Louisville a 59% chance of winning against Duke.

More: Duke vs. Louisville Simulated 10K Times

Duke vs. Louisville Odds

We have sourced the best betting odds in America for this game, which are listed here:

• Spread: Louisville -5.5 (-110), Duke +5.5 (-110)
• Moneyline: Louisville -194, Duke +180
• Total: Over/Under 47 (-110/-110)

Odds are correct at the time of publication and subject to change.

Louisville is the -5.5 favorite against Duke, with -110 at PointsBet the best odds currently available.

For the underdog Duke (+5.5) to cover the spread, PointsBet also has the best odds currently on the market at -110.

FanDuel Sportsbook currently has the best moneyline odds for Louisville at -194. That means you can risk $194 to win $100, for a total payout of $294, if it gets the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for Duke at +180, where you can bet $100 to profit $180, earning a total payout of $280, if it wins.

The Over/Under for total points scored sits at 47 with PointsBet, which currently has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Duke (+5.5) has a 55% chance of covering the spread, while the 47-point Over/Under has a 52% chance of going Under.

Calling all football fans! If you are yet to sign up with DraftKings Sportsbook, today is the day! Click here to sign up, and then place a $5 wager on Duke vs. Louisville to receive $200 in bonus bets!

More: Free Prop Picks

Best Bets: Duke vs. Louisville

• Spread: Duke +5.5 @ -110 via PointsBet (55% probability)
• Moneyline: Duke @ +180 via DraftKings Sportsbook (5.2% edge) 🔥
• Total: Under 47 @ -110 via PointsBet (52% probability)

When you see a 🔥, that means you've found one of Dimers' best bets of the day across any sport.

Our best bets are based on complex simulations and gambling intelligence to help you make better decisions with your state's legal sportsbooks.

While Louisville is more likely to win the game, according to DimersBOT, taking Duke moneyline is the best option because of the 5.2% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published here at Dimers.com is crucial to being profitable in the long run.

Duke vs. Louisville Prediction

Dimers.com's predicted final score for Duke vs. Louisville at L&N Federal Credit Union Stadium this Saturday has Louisville winning 24-21.

Click or tap on See Matchup for more information.

Dimers has full coverage of this week's Duke vs. Louisville game, including pregame predictions, the best picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this page for any changes to our betting insights before Duke vs. Louisville on Saturday October 28, 2023.

Another great way to make the most of this Duke vs. Louisville game is by using the latest DraftKings promo, where a bet as small as $5 guarantees you $200 in bonus bets, plus an extra few SGP tokens.

Duke vs. Louisville Preview

Saturday's matchup between Louisville and Duke in College Football at L&N Federal Credit Union Stadium is scheduled to commence at 3:30PM ET.

• Who: Duke vs. Louisville
• Date: Saturday October 28, 2023
• Time: 3:30PM ET / 12:30PM PT
• Venue: L&N Federal Credit Union Stadium

How to Bet on Duke vs. Louisville

Want to join an online sportsbook and start betting on College Football now? We've got access to the best available welcome offers for every legal betting state, including Bet365, where you get $150 in bonus bets for signing up and bettting $5 on Duke vs. Louisville.

Conclusion

This comprehensive game preview includes our Duke vs. Louisville prediction and College Football odds.

Dimers' picks are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Duke vs. Louisville predictions can help you make informed decisions, it's crucial that you gamble responsibly and manage your finances effectively.

To increase your likelihood to be a responsible gambler, we recommended reading this full guide to Kentucky sports betting as well as utilizing these .Kentucky sportsbook promos that can get you started off on the right foot.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Want More CFB Predictions Like This?

To get more NCAA Football betting previews like you've just read for Duke vs. Louisville, all you've gotta do is visit our College Football Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the best CFB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – check out our College Football picks and predictions.

In addition to our leading CFB predictions, we also feature the best CFB prop bets today, projecting passing yards, touchdowns, and more against the best odds available every single day of the CFB season.