Dodgers vs. Cubs Prediction and Odds - Apr 21, 2023

The Chicago Cubs square off with the Los Angeles Dodgers in MLB action at Wrigley Field on Friday, beginning at 2:20PM ET.

The Cubs will send Drew Smyly (1-1, 4.70 ERA) to the mound, while the Dodgers will counter with Julio Urías (3-1, 1.90 ERA).

Dimers' free betting picks for Dodgers vs. Cubs, plus game predictions and best odds, are detailed below.

Who will win Dodgers vs. Cubs?

Based on cutting-edge machine learning and data, Dimers.com has simulated Friday's Dodgers-Cubs MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Dodgers a 55% chance of winning against the Cubs.

More: Dodgers vs. Cubs Simulated 10,000 Times

Dodgers vs. Cubs Odds

• Run Line: Cubs +1.5 (-110), Dodgers -1.5 (-110)
• Moneyline: Cubs +140, Dodgers -164
• Total: Over/Under 9.5 (-110/-106)

Run Line, Moneyline and Over/Under

The Cubs are currently +1.5 underdogs versus the Dodgers, with -110 at PointsBet the best odds currently available.

For the favored Dodgers (-1.5) to cover the run line, PointsBet also has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Cubs at +140. That means you can bet $100 to profit $140, earning a total payout of $240, if they win.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Dodgers at -164, where you can risk $164 to win $100, for a total payout of $264, if they come out on top.

The Over/Under sits at 9.5 with PointsBet, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -106.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 57% chance of covering the run line, while the 9.5-run Over/Under is a 54% chance of going Under.

More: Live Scores for All Major Sports

Best Bets for Dodgers vs. Cubs

• Run Line: Cubs +1.5 @ -110 via PointsBet (57% probability) 🔥
• Moneyline: Cubs @ +140 via BetMGM (2.9% edge)
• Total: Under 9.5 @ -106 via FanDuel Sportsbook (54% probability)

If you see a 🔥, you know you've found one of Dimers' best free picks today across all major pro and college sports.

Dimers' best bets are based on complex modeling and wagering expertise to help you make more informed decisions with your state's legal sportsbooks.

While the Dodgers are more likely to win the game, according to DimersBOT, betting on the Cubs moneyline is the best option due to the 2.9% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers.com is one of the keys to being profitable in the long run.

Dodgers vs. Cubs Betting Guide

Click or tap on See Matchup for more.

Dimers has full betting coverage of Friday's Dodgers-Cubs matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep checking this article for the latest betting insights ahead of Dodgers vs. Cubs on Friday April 21, 2023.

Dodgers vs. Cubs 2023 Game Info

Friday's action between the Cubs and Dodgers at Wrigley Field is scheduled to begin at 2:20PM ET.

• Who: Los Angeles Dodgers vs. Chicago Cubs
• Date: Friday April 21, 2023
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

Want to join an online sportsbook and start betting on MLB? We've reviewed the best available sign-up offers for every legal betting state.

Calling Our Shot ⚾️ Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Want more MLB previews like this?

To get more MLB betting previews like you've just read for Dodgers vs. Cubs, all you've gotta do is visit our MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can publish the most comprehensive MLB betting previews out there. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

As well as MLB game picks and predicitons, we also provide the best MLB prop bets for today, with our projections for home runs, RBIs, and more lined up against the best available sportsbook odds every single day of the MLB season.

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the World Series, with our data-led probabilities matched against the best odds on the market.