Diamondbacks vs. White Sox Prediction for MLB Wednesday [9/27/2023]

The Chicago White Sox will square off with the Arizona Diamondbacks in MLB action at Guaranteed Rate Field on Wednesday, beginning at 2:10PM ET.

The White Sox will send Luis Patiño (0-0, 4.24 ERA) to the mound, up against Brandon Pfaadt (2-9, 6.08 ERA) for the Diamondbacks.

Dimers' top betting picks for Diamondbacks vs. White Sox, plus game predictions and best odds, are detailed below.

Who Will Win: Diamondbacks vs. White Sox

Using cutting-edge computer power and data, Dimers.com has simulated Wednesday's Diamondbacks-White Sox MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Diamondbacks a 60% chance of getting the W against the White Sox.

More: Betting Analysis for Diamondbacks vs. White Sox

Diamondbacks vs. White Sox Odds [9/27]

• Run Line: White Sox +1.5 (+105), Diamondbacks -1.5 (-120)
• Moneyline: White Sox +160, Diamondbacks -190
• Total: Over/Under 9 (-115/-104)

The White Sox are currently +1.5 underdogs against the Diamondbacks, with +105 at DraftKings Sportsbook the best odds currently available.

For the favored Diamondbacks (-1.5) to cover the run line, PointsBet has the best odds currently on the market at -120.

DraftKings Sportsbook currently has the best moneyline odds for the White Sox at +160. That means you can bet $100 to profit $160, earning a total payout of $260, if they win.

Elsewhere, PointsBet currently has the best moneyline odds for the Diamondbacks at -190, where you can risk $190 to win $100, for a total payout of $290, if they come out on top.

The Over/Under for total runs scored sits at 9 with PointsBet, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) have a 52% chance of covering the run line, while the 9-run Over/Under has a 60% chance of going Over.

More: Best Prop Bets Today

Best Bets: Diamondbacks vs. White Sox

• Run Line: White Sox +1.5 @ +105 via DraftKings Sportsbook (52% probability)
• Moneyline: White Sox @ +160 via DraftKings Sportsbook (1.6% edge)
• Total: Over 9 @ -115 via PointsBet (60% probability) 🔥

When you see a 🔥, that means it's one of Dimers' best bets of the day across all major pro and college sports.

Dimers' best bets are based on world-class modeling and wagering intelligence to bring you the best possible plays 24/7/365.

While the Diamondbacks are more likely to win the game, according to DimersBOT, taking the White Sox moneyline is the best option because of the 1.6% edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at Dimers is one of the keys to achieving long-term profitability.

Diamondbacks vs. White Sox Prediction

Dimers.com predicts that the Diamondbacks are more likely to beat the White Sox in the MLB game on Wednesday.

This prediction is backed by comprehensive data-driven analysis, with the Diamondbacks boasting a 60% probability of winning after conducting 10,000 game simulations.

Click or tap on See Matchup to find out more.

Dimers has full coverage of Wednesday's Diamondbacks-White Sox game, including pregame predictions, top betting picks, and live scores.

Remember, DimersBOT updates frequently, so keep checking this article for the latest betting analysis ahead of Diamondbacks vs. White Sox on Wednesday September 27, 2023.

Diamondbacks vs. White Sox 2023

Wednesday's MLB game between the White Sox and Diamondbacks at Guaranteed Rate Field is scheduled to begin at 2:10PM ET.

• Who: Arizona Diamondbacks vs. Chicago White Sox
• Date: Wednesday September 27, 2023
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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Make Informed Sports Betting Decisions with Dimers

Dimers' predictions are made after 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While these Diamondbacks vs. White Sox predictions can help you make informed decisions, it's crucial that you only bet what you can afford to lose and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What Other MLB Games Are on Today?

Now you've got the 411 on Diamondbacks vs. White Sox, take a look at the latest predictions for all MLB games via our MLB picks and predictions, where you can find probabilities and odds, and our best bets for each and every MLB matchup. Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good!

In addition to our leading MLB predictions, we also feature the best MLB prop bets today, projecting home runs, RBIs, and more against the best odds available every day of the MLB season.

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the World Series, with our data-driven probabilities compared to the best odds on the market.