Diamondbacks vs. Astros Prediction and Odds - Sep 27, 2022

The Houston Astros and Arizona Diamondbacks lock horns in MLB at Minute Maid Park on Tuesday, starting at 8:10PM ET.

The Astros will have Luis Garcia (13-8, 3.90 ERA) start, while the Diamondbacks are going with Zach Davies (2-4, 4.03 ERA).

Dimers' top betting picks for Diamondbacks vs. Astros, as well as game predictions and best odds, are detailed below.

Who will win Diamondbacks vs. Astros?

Using cutting-edge machine learning and data, Dimers.com has simulated Tuesday's Diamondbacks-Astros MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Astros a 64% chance of beating the Diamondbacks.

More: Diamondbacks vs. Astros Simulated 10K Times

Diamondbacks vs. Astros Game Odds

• Run Line: Astros -1.5 (-105), Diamondbacks +1.5 (-111)
• Moneyline: Astros -200, Diamondbacks +188
• Total: Over/Under 8 (-115/-105)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites against the Diamondbacks, with -105 at BetMGM the best odds currently available.

For the underdog Diamondbacks (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -111.

BetMGM currently has the best moneyline odds for the Astros at -200. That means you can risk $200 to win $100, for a total payout of $300, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Diamondbacks at +188, where you can put down $100 to profit $188, earning a total payout of $288, if they win.

The Over/Under sits at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

As always, check out all of the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Diamondbacks (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 8 runs is a 60% chance of going Over.

More: Free Prop Picks

Best Bets for Diamondbacks vs. Astros

• Run Line: Diamondbacks +1.5 @ -111 via FanDuel Sportsbook (54% probability)
• Moneyline: Diamondbacks @ +188 via FanDuel Sportsbook (1.6% edge)
• Total: Over 8 @ -115 via Caesars Sportsbook (60% probability) 🔥

Every time you see a 🔥, that means you've found one of our best free picks today across all sports.

Dimers' best bets are based on complex modeling and gambling expertise to bring you the best possible plays 24/7.

While the Astros are more likely to win the game, according to DimersBOT, taking the Diamondbacks moneyline is the best option due to the 1.6% edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers is one of the keys to achieving long-term profitability.

Diamondbacks vs. Astros Probabilities

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Dimers has full betting coverage of Tuesday's Diamondbacks-Astros matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep checking this article for any changes to our betting insights ahead of Diamondbacks vs. Astros on Tuesday September 27, 2022.

Diamondbacks vs. Astros 2022 Game Info

Tuesday's game between the Astros and Diamondbacks at Minute Maid Park is scheduled to begin at 8:10PM ET.

• Who: Arizona Diamondbacks vs. Houston Astros
• Date: Tuesday September 27, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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Want more MLB predictions like this?

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We use the power of predictive analytics to find value in the markets so we can publish the best MLB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.