Pistons vs. Spurs Prediction: Detroit Predicted to Win Friday's NBA Game [2/21/2025]

The San Antonio Spurs will take on the Detroit Pistons in NBA action at Moody Center on Friday, commencing at 8:30PM ET.

Based on updated simulations and today’s injury updates, Dimers' advanced NBA model (see Dimers Pro for full access) predicts the Pistons as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Detroit-San Antonio game 10,000 times," said Damien Souness from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Pistons' chance of winning is 63%, while the Spurs' is 37%."

This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like De'Aaron Fox, Devin Vassell and Stephon Castle, while the Pistons will be led by Cade Cunningham, Tobias Harris and Jalen Duren.

For further insights into Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Pistons vs. Spurs predictions page.

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Spurs vs. Pistons Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data analysis, we have simulated the result of Friday's NBA game between the Pistons and Spurs 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Pistons a 63% chance of beating the Spurs. Our predicted final score has the Pistons winning 119-115.

According to our model, the Spurs (+4.5) have a 52% chance of covering the spread, while the 235.5-point over/under has a 52% chance of staying under.

Pistons vs. Spurs Odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Pistons vs. Spurs Picks and Best Bets

Our model's strongest edge in today's Pistons vs. Spurs matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Pistons vs. Spurs Player Props

NBA player props are an enjoyable way to wager on Friday's Pistons vs. Spurs game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Moody Center.

Cade Cunningham is expected to lead the Pistons with 26 points, 6 rebounds and 10 assists, while De'Aaron Fox is projected to have 24 points, 4 rebounds and 5 assists for the Spurs.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Projected Box Scores for Every NBA Game

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Pistons vs. Spurs Game-Day Updates and Essential Details

Friday's action between the Spurs and Pistons at Moody Center is scheduled to commence at 8:30PM ET.

• Who: Detroit Pistons vs. San Antonio Spurs
• Date: Friday, February 21, 2025
• Time: 8:30PM ET/5:30PM PT
• Venue: Moody Center

Dimers.com's in-depth preview of Friday's Pistons vs. Spurs matchup includes our prediction, picks and the latest betting odds.

Before making any Detroit vs. San Antonio picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pistons, with a 63% win probability, will likely beat the Spurs on Friday.

AI and automation have enhanced this article to quickly deliver accurate Pistons vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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