Detroit Lions vs. San Francisco 49ers Prediction, Odds, NFL Picks - NFC Championship Game [2024]

The San Francisco 49ers will face the Detroit Lions in the NFC Championship Game of the NFL Playoffs at Levi's Stadium on Sunday, commencing at 6:30PM ET.

Dimers.com's in-depth betting preview for this week's Lions vs. 49ers matchup includes the latest betting odds, as well as our predictions and picks for the game.

Lions vs. 49ers Prediction: Model Picks Lions To Cover The Spread

We have used advanced machine learning and data analysis to simulate the result of Sunday's NFL game between the Lions and 49ers 10,000 times, in line with our coverage of NFL predictions.

Our independent predictive analytics model currently gives the 49ers a 70% chance of beating the Lions, and our predicted final score has the 49ers winning 28-22.

According to our model, the Lions (+7) have a 57% chance of covering the spread, while the Over/Under total of 50.5 points has a 53% chance of going under.

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Lions vs. 49ers Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Lions	49ers
Spread	+7 (-110)	-7 (-105)
Moneyline	+275	-310
Total	o50.5 (-115)	u50.5 (-105)

• The 49ers are listed as -7 favorites against the Lions, with -105 at BetMGM Sportsbook the best odds currently available.
• For the underdog Lions (+7) to cover the spread, FanDuel Sportsbook has the best odds currently on offer at -110.
• DraftKings Sportsbook currently has the best moneyline odds for the 49ers at -310, which means you can risk $310 to win $100 for a total payout of $410 if they get the W.
• FanDuel currently has the best moneyline odds for the Lions at +275, where you can bet $100 to profit $275, earning a total payout of $375 if they win.
• The Over/Under for total points scored sits at 50.5 with FanDuel, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

All odds are correct at the time of publication and are subject to change.

As always, make sure you check all of the sportsbooks that are available in your state for the best NFL odds and lines.

Lions vs. 49ers Picks

By comparing our probabilities to the odds listed above, we have determined the best betting picks for this game:

Bet Type	Our Pick	Best Odds
Spread	Lions +7	-110 🔥
Moneyline	Lions	+275
Total	Under 50.5	-105

When you see a 🔥, that means it's one of Dimers' best bets of the day across all major pro and college sports.

While the 49ers are more likely to win the game, betting on the Lions moneyline is the best option due to the 3.4% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers is pivotal to achieving long-term profitability as a sports bettor.

Our NFL best bets are based on detailed simulations and betting expertise to serve you the best possible plays every week of the season.

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Lions vs. 49ers TD Scorers

Who will score the first touchdown in Lions vs. 49ers?

According to our model, San Francisco's Christian McCaffrey is most likely to score the first touchdown in Lions vs. 49ers.

Our projections give McCaffrey a 19.3% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 72.3% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Detroit Lions

Player	First TD Probability
Jahmyr Gibbs	8.8%
Amon-Ra St. Brown	7.1%
David Montgomery	7.0%
Sam LaPorta	6.4%
Jameson Williams	4.1%

San Francisco 49ers

Player	First TD Probability
Christian McCaffrey	19.3%
Deebo Samuel	9.8%
Brandon Aiyuk	8.1%
George Kittle	7.6%
Ray-Ray McCloud	2.9%

Anytime Touchdown Scorer Predictions

Detroit Lions

Player	Anytime TD Probability
Jahmyr Gibbs	41.5%
Amon-Ra St. Brown	36.0%
David Montgomery	35.0%
Sam LaPorta	32.1%
Jameson Williams	23.8%

San Francisco 49ers

Player	Anytime TD Probability
Christian McCaffrey	72.3%
Deebo Samuel	44.9%
Brandon Aiyuk	39.8%
George Kittle	36.3%
Jauan Jennings	16.3%

Lions vs 49ers Player Props

Here, you will find detailed projections for all of the key offensive players from the Lions and 49ers, including passing, rushing and receiving yards.

Lions vs. 49ers Quarterbacks

Of the starting quarterbacks, the Lions' Jared Goff is projected for 243 passing yards. The 49ers' Brock Purdy is expected to throw for a whopping 306 yards.

Player	Proj. Pass Yards
Jared Goff (DET)	243 yds
Brock Purdy (SF)	306 yds

Lions Rushing

Player	Proj. Rush Yards
David Montgomery	54 yds
Jahmyr Gibbs	45 yds
Craig Reynolds	7 yds

49ers Rushing

Player	Proj. Rush Yards
Christian McCaffrey	101 yds
Deebo Samuel	12 yds
Brock Purdy	11 yds

Lions Receiving

Player	Proj. Rec. Yards
Amon-Ra St. Brown	86 yds
Sam LaPorta	48 yds
Jameson Williams	31 yds
Josh Reynolds	26 yds
Jahmyr Gibbs	17 yds

49ers Receiving

Player	Proj. Rec. Yards
Brandon Aiyuk	73 yds
George Kittle	61 yds
Deebo Samuel	61 yds
Christian McCaffrey	41 yds
Jauan Jennings	27 yds

Remember, our model updates often, so refresh this page for any changes to our betting insights before the Lions vs. 49ers on Sunday January 28, 2024.

Lions vs. 49ers Game Information

Sunday's game between the 49ers and Lions at Levi's Stadium is scheduled to begin at 6:30PM ET.

• Who: Detroit Lions vs. San Francisco 49ers
• Date: Sunday January 28, 2024
• Time: 6:30PM ET / 3:30PM PT
• Venue: Levi's Stadium

Our full coverage of Lions vs. 49ers includes pregame predictions, betting picks, and live updates.

How to Bet on Lions vs. 49ers

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Conclusion

This preview article has been partially generated using automated processes and AI technology. Our goal is to provide timely and accurate updates on this week's Lions vs. 49ers clash, and automation assists in data collection, analysis, and formatting. Human editing and quality control are performed to ensure the content meets our editorial guidelines.

Dimers' picks and predictions are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods. While these Lions vs. 49ers picks can help you make informed decisions, it's important that you gamble responsibly and manage your bankroll effectively.

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