Lions vs. Colts Prediction: Detroit Predicted to Win in NFL Week 12 [2024]

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Written by Dave Garofolo

Our expert prediction for Sunday's Detroit Lions vs Indianapolis Colts matchup.

Detroit Lions-Indianapolis Colts Predictions and Game Preview.
Lucas Oil Stadium sets the stage for the NFL matchup between the Detroit Lions and Indianapolis Colts this Sunday.

The Indianapolis Colts and Detroit Lions will meet in Week 12 of the NFL season at Lucas Oil Stadium on Sunday, starting at 1:00PM ET.

Based on the latest simulations, Dimers' advanced NFL model (see Dimers Pro for full access) predicts the Lions as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Detroit-Indianapolis game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Lions with a win probability of 73%, while the Colts have 27%."

This updated Lions vs. Colts betting preview builds on my early Lions vs. Colts prediction that I released at the start of the week.

For a closer look at today’s game, including the predicted score, best bets and player prop picks, visit our interactive Lions vs. Colts predictions page.

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Lions vs. Colts Game-Day Updates and Essential Details

The NFL Week 12 matchup between the Colts and Lions at Lucas Oil Stadium is scheduled to commence at 1:00PM ET.

Dimers.com's comprehensive preview of this week's Lions vs. Colts matchup includes our prediction, picks and the latest betting odds.

Before making any Detroit vs. Indianapolis picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

Lions vs. Colts Predictions

Using innovative machine learning and data, we have simulated the result of Sunday's NFL matchup between the Lions and Colts 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the Lions a 73% chance of beating the Colts in Week 12 of the NFL season. Our predicted final score has the Lions winning 28-21.

According to our model, the bookmakers have got it right, and the Lions and Colts each have a 50% chance of covering the spread, while the over/under total of 50.5 points also has an equal 50-50 chance of hitting.

 

In addition to our Lions vs. Colts predictions, we've also prepared the following for today’s action:

Lions vs. Colts Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Lions Colts
Spread -7 (-110) +7 (-102)
Moneyline -360 +310
Total o50.5 (-105) u50.5 (-110)

All odds are correct at the time of publication and are subject to change.

Lions vs. Colts Picks

Our model's strongest edge in today's Lions vs. Colts matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Lions vs. Colts TD Scorers

Who will score the first touchdown in Lions vs. Colts?

According to our model, Detroit's David Montgomery is most likely to score the first touchdown in Lions vs. Colts.

Our projections give Montgomery a 15.4% chance of scoring the first TD at Lucas Oil Stadium, while the Lions RB is a 62.2% chance of registering an anytime touchdown.

First Touchdown Scorer Predictions

Detroit Lions

Player First TD Probability
David Montgomery 15.4%
Jahmyr Gibbs 12.0%
Amon-Ra St. Brown 9.9%

Indianapolis Colts

Player First TD Probability
Jonathan Taylor 11.0%
Anthony Richardson 8.8%
Josh Downs 5.7%

Anytime Touchdown Scorer Predictions

Detroit Lions

Player Anytime TD Probability
David Montgomery 62.2%
Jahmyr Gibbs 53.1%
Amon-Ra St. Brown 44.6%

Indianapolis Colts

Player Anytime TD Probability
Jonathan Taylor 49.9%
Anthony Richardson 41.1%
Josh Downs 28.8%

For a complete analysis of the most likely first and anytime TD scorers this week, see our NFL Week 12 touchdown scorer predictions

Lions vs Colts Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Lions and Colts. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Lions-Colts page now to access every player prop projection.

Lions vs. Colts Quarterbacks

Of the starting quarterbacks, the Lions' Jared Goff is projected to throw for more yards than the Colts' Anthony Richardson.

Lions Rushing

Jahmyr Gibbs, David Montgomery and Jared Goff are projected to be the leading rushers for the Lions.

Player Position
Jahmyr Gibbs RB
David Montgomery RB
Jared Goff QB

Colts Rushing

Jonathan Taylor, Anthony Richardson and Trey Sermon are expected to lead the Colts in rushing yards.

Player Position
Jonathan Taylor RB
Anthony Richardson QB
Trey Sermon RB

Lions Receiving

Amon-Ra St. Brown, Jameson Williams, Sam LaPorta, Jahmyr Gibbs and Tim Patrick are projected to top the receiving yards for the Lions.

Player Position
Amon-Ra St. Brown WR
Jameson Williams WR
Sam LaPorta TE
Jahmyr Gibbs RB
Tim Patrick WR

Colts Receiving

Michael Pittman, Josh Downs, Alec Pierce, Adonai Mitchell and Jonathan Taylor are projected to lead the Colts in receiving yards.

Player Position
Michael Pittman WR
Josh Downs WR
Alec Pierce WR
Adonai Mitchell WR
Jonathan Taylor RB

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Conclusion

We predict the Lions, with a 73% win probability, will likely beat the Colts on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Lions vs. Colts insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on NFL

Keep up with the latest NFL betting news, NFL best bets and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date projections for the Super Bowl, AFC, NFC and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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