Detroit Lions vs. Indianapolis Colts Early Predictions for NFL Week 12: Odds, Picks and Preview [2024]

The Indianapolis Colts and Detroit Lions will face off against each other in Week 12 of the NFL season at Lucas Oil Stadium on Sunday, November 24, 2024, starting at 1:00PM ET.

Early simulation results from Dimers' proven NFL model project the Lions as the most likely winner of this game.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Lions vs. Colts predictions page.

Lions vs. Colts Week 12 Details

The NFL Week 12 matchup between the Colts and Lions at Lucas Oil Stadium is scheduled for November 24, 2024.

• Who: Detroit Lions vs. Indianapolis Colts
• Date: Sunday, November 24, 2024
• Time: 1:00PM ET/10:00AM PT
• Venue: Lucas Oil Stadium

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Lions vs. Colts Opening Odds

We've researched the best betting odds across America for this Week 12 game, detailed below:

• Spread: Lions -2.5 (-112), Colts +2.5 (-108)
• Moneyline: Lions -135, Colts +114
• Total: Over/Under 48.5 (-110/-110)

Detroit vs. Indianapolis Early Predictions

Leveraging trusted machine learning and analysis, we have simulated the Lions vs. Colts game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight Up Win Probabilities: Lions 57%, Colts 43%
• Predicted Final Score: Lions 25-23 Colts
• Spread: Lions (-2.5) 58%, Colts (+2.5) 42%
• Total Points (48.5): Over 45%, Under 55%

As of November 17, 2024, these Lions-Colts predictions reflect the latest data and insights available.

Conclusion

We predict the Lions, with a 57% win probability, will likely beat the Colts in Week 12 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Lions vs. Colts game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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