Lions vs. Cardinals Prediction: Detroit Predicted to Win Following Latest Data Analysis for NFL Week 3 [2024]

The Arizona Cardinals will take on the Detroit Lions in NFL Week 3 action at State Farm Stadium on Sunday, beginning at 4:25PM ET.

Based on updated simulations, Dimers' proven NFL model (see Dimers Pro for full access) predicts the Lions as the most likely winner of the game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Lions-Cardinals game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Lions with a win probability of 58%, while the Cardinals have 42%."

Lions vs. Cardinals Game-Day Updates and Essential Details

The NFL Week 3 action between the Cardinals and Lions at State Farm Stadium is scheduled to commence at 4:25PM ET.

• Who: Detroit Lions vs. Arizona Cardinals
• Date: Sunday, September 22, 2024
• Time: 4:25PM ET/1:25PM PT
• Venue: State Farm Stadium
• Tickets: Get tickets for the game on Ticketmaster
• Merchandise: Buy Cardinals and Lions gear at Fanatics
• Live Stream: Watch this game on FOX via Hulu or FuboTV

Dimers.com's full preview of Sunday's Lions vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Cardinals vs. Lions picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Lions vs. Cardinals Predictions

Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's NFL game between the Lions and Cardinals 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Lions a 58% chance of defeating the Cardinals in Week 3 of the NFL season. Our predicted final score has the Lions winning 27-24.

According to our model, the Cardinals (+3) have a 56% chance of covering the spread, while the over/under total of 51.5 points has an equal 50-50 chance of hitting.

Lions vs. Cardinals Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Lions	Cardinals
Spread	-3 (-105)	+3 (-115)
Moneyline	-144	+125
Total	o51.5 (-110)	u51.5 (-110)

All odds are correct at the time of publication and are subject to change.

Lions vs. Cardinals Picks

Our model's biggest edge in the Lions vs. Cardinals matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best NFL picks for every game throughout the season.

Unlimited access to our picks, including this one, is available via Dimers Pro.

Lions vs. Cardinals TD Scorers

Who will score an anytime touchdown in Lions vs. Cardinals?

According to our model, Arizona's James Conner is most likely to score the first TD in Lions vs. Cardinals.

Our projections give Conner an 11.6% chance of scoring the first TD at State Farm Stadium, while the Cardinals RB is a 51.9% chance of registering an anytime touchdown.

First Touchdown Scorer Predictions

Detroit Lions

Player	First TD Probability
David Montgomery	11.5%
Jahmyr Gibbs	11.2%
Amon-Ra St. Brown	8.2%

Arizona Cardinals

Player	First TD Probability
James Conner	11.6%
Marvin Harrison	8.0%
Trey McBride	6.4%

Anytime Touchdown Scorer Predictions

Detroit Lions

Player	Anytime TD Probability
David Montgomery	50.9%
Jahmyr Gibbs	50.1%
Amon-Ra St. Brown	39.7%

Arizona Cardinals

Player	Anytime TD Probability
James Conner	51.9%
Marvin Harrison	39.1%
Trey McBride	33.1%

Lions vs Cardinals Player Props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Lions and Cardinals. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Lions-Cardinals page now to access every player prop projection.

Lions vs. Cardinals Quarterbacks

Of the starting quarterbacks, the Lions' Jared Goff is projected to throw for more yards than the Cardinals' Kyler Murray.

Lions Rushing

Jahmyr Gibbs, David Montgomery and Sione Vaki are projected to be the leading rushers for the Lions.

Player	Position
Jahmyr Gibbs	RB
David Montgomery	RB
Sione Vaki	RB

Cardinals Rushing

James Conner, Kyler Murray and Trey Benson are expected to lead the Cardinals in rushing yards.

Player	Position
James Conner	RB
Kyler Murray	QB
Trey Benson	RB

Lions Receiving

Amon-Ra St. Brown, Jameson Williams, Sam LaPorta, Jahmyr Gibbs and Kalif Raymond are projected to top the receiving yards for the Lions.

Player	Position
Amon-Ra St. Brown	WR
Jameson Williams	WR
Sam LaPorta	TE
Jahmyr Gibbs	RB
Kalif Raymond	WR

Cardinals Receiving

Marvin Harrison, Trey McBride, Greg Dortch, Michael Wilson and Elijah Higgins are projected to lead the Cardinals in receiving yards.

Player	Position
Marvin Harrison	WR
Trey McBride	TE
Greg Dortch	WR
Michael Wilson	WR
Elijah Higgins	TE

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Conclusion

We predict the Lions, with a 58% win probability, will likely beat the Cardinals in Week 3 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Lions vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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