DePaul vs. Northwestern Prediction: Northwestern Predicted to Win College Basketball Matchup [12/21/2024]

College basketball action continues on Saturday at 4:00PM ET as DePaul takes on the favored Northwestern in college basketball action at Welsh-Ryan Arena.

Based on the latest simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Northwestern as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's DePaul-Northwestern game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Northwestern is more likely to win, while DePaul has a lower chance of victory."

For a closer look at Saturday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive DePaul vs. Northwestern predictions page.

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DePaul vs. Northwestern Game-Day Updates and Essential Details

Saturday's college basketball game between Northwestern and DePaul at Welsh-Ryan Arena is scheduled to start at 4:00PM ET.

• Who: DePaul vs. Northwestern
• Date: Saturday, December 21, 2024
• Time: 4:00PM ET/1:00PM PT
• Venue: Welsh-Ryan Arena
• Tickets: Get tickets for the game on Ticketmaster

Dimers.com's comprehensive preview of Saturday's DePaul vs. Northwestern matchup includes our prediction, picks and the latest betting odds.

Before making any DePaul vs. Northwestern picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

DePaul vs. Northwestern Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data, we have simulated the result of Saturday's NCAA basketball matchup between DePaul and Northwestern 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model gives Northwestern a 73% chance of defeating DePaul. Our predicted final score has Northwestern winning 72-66.

According to our model, DePaul (+6.5) has a 51% chance of covering the spread, while the 135.5-point over/under has a 53% chance of going over.

DePaul vs. Northwestern Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	DePaul	Northwestern
Spread	+6.5 (-105)	-6.5 (-110)
Moneyline	+235	-265
Total	o135.5 (-105)	u135.5 (-112)

All odds are correct at the time of publication and are subject to change.

DePaul vs. Northwestern Picks

Our model's biggest edge in today's DePaul vs. Northwestern matchup is on the spread.

Our expert predictions, matched against the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Conclusion

We predict Northwestern, with a 73% win probability, will likely beat DePaul on Saturday.

AI and automation have enhanced this article to quickly deliver accurate DePaul vs. Northwestern insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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