Cubs vs. Cardinals Prediction and Odds - Sep 3, 2022

The St. Louis Cardinals and Chicago Cubs clash in MLB at Busch Stadium on Saturday, starting at 7:15PM ET.

Adam Wainwright (9-9, 3.09 ERA) will start for the Cardinals, while the Cubs will counter with Drew Smyly (5-7, 3.24 ERA).

Dimers' best betting picks for Cubs vs. Cardinals, as well as game predictions and betting odds, are detailed in this article.

Who will win Cubs vs. Cardinals?

Using trusted machine learning and data, Dimers.com has simulated Saturday's Cubs-Cardinals MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Cardinals a 65% chance of beating the Cubs.

More: Cubs vs. Cardinals Simulated 10,000 Times

Cubs vs. Cardinals Odds

• Run Line: Cardinals -1.5 (+105), Cubs +1.5 (-120)
• Moneyline: Cardinals -200, Cubs +180
• Total: Over/Under 7.5 (+100/-120)

Run Line, Moneyline and Over/Under

The Cardinals are currently -1.5 favorites against the Cubs, with +105 at DraftKings Sportsbook the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, BetMGM has the best odds currently on the market at -120.

BetMGM currently has the best moneyline odds for the Cardinals at -200, which means you can risk $200 to win $100, for a total payout of $300, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Cubs at +180, where you can put down $100 to profit $180, earning a total payout of $280, if they win.

The Over/Under sits at 7.5 with BetMGM, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all of the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 7.5 runs is a 53% chance of going Over.

More: Best Prop Bets Today

Best Bets for Cubs vs. Cardinals

• Run Line: Cubs +1.5 @ -120 via BetMGM (54% probability)
• Moneyline: Cubs @ +180 via DraftKings Sportsbook
• Total: Over 7.5 @ +100 via BetMGM (53% probability)

Dimers' best bets are based on complex modeling and gambling expertise to bring you the best possible plays every day of the year.

While the Cardinals are more likely to win the game, according to DimersBOT, taking the Cubs moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is one of the keys to being a profitable sports bettor in the long run.

Cubs vs. Cardinals Prediction

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Dimers has full coverage of Saturday's Cubs-Cardinals matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis before Cubs vs. Cardinals on Saturday September 3, 2022.

Cubs vs. Cardinals 2022 Game Info

Saturday's action between the Cardinals and Cubs at Busch Stadium is scheduled to begin at 7:15PM ET.

• Who: Chicago Cubs vs. St. Louis Cardinals
• Date: Saturday September 3, 2022
• Time: 7:15PM ET / 4:15PM PT
• Venue: Busch Stadium

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What other MLB games are on today?

The Cubs and Cardinals aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single MLB game in our MLB Bet Hub section.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.