Cubs vs. Astros Prediction and Odds - May 15, 2023

The Houston Astros take on the Chicago Cubs in MLB action at Minute Maid Park on Monday, commencing at 8:10PM ET.

Framber Valdez (3-4, 2.38 ERA) will get the ball for the Astros, up against Jameson Taillon (0-2, 6.41 ERA) for the Cubs.

Dimers' best betting picks for Cubs vs. Astros, plus game predictions and best odds, are featured below.

Who Will Win: Cubs vs. Astros

Using high-tech machine learning and data, Dimers.com has simulated Monday's Cubs-Astros MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Astros a 64% chance of beating the Cubs.

More: Betting Picks for Cubs vs. Astros

Cubs vs. Astros Current Odds

• Run Line: Astros -1.5 (+110), Cubs +1.5 (-125)
• Moneyline: Astros -190, Cubs +175
• Total: Over/Under 7.5 (-115/-104)

Run Line, Moneyline and Over/Under

The Astros are currently -1.5 favorites against the Cubs, with +110 at BetMGM the best odds currently available.

For the underdog Cubs (+1.5) to cover the run line, PointsBet has the best odds currently on offer at -125.

BetMGM currently has the best moneyline odds for the Astros at -190, which means you can risk $190 to win $100, for a total payout of $290, if they get the W.

Meanwhile, PointsBet currently has the best moneyline odds for the Cubs at +175, where you can put down $100 to profit $175, earning a total payout of $275, if they win.

The Over/Under is set at 7.5 with PointsBet, which currently has the best odds for the Over at -115, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, check out all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) have a 54% chance of covering the run line, while the Over/Under total of 7.5 runs has a 54% chance of going Over.

More: Free Prop Picks

Best Bets for Cubs vs. Astros

• Run Line: Cubs +1.5 @ -125 via PointsBet (54% probability)
• Moneyline: Cubs @ +175 via PointsBet
• Total: Over 7.5 @ -115 via PointsBet (54% probability)

Our best bets are based on world-class modeling and wagering expertise to bring you the best possible plays 24/7/365.

While the Astros are more likely to win the game, according to DimersBOT, taking the Cubs moneyline is the best option due to the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen here at Dimers.com is pivotal to being profitable in the long run.

Cubs vs. Astros Prediction

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Dimers has full betting coverage of Monday's Cubs-Astros matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates often, so refresh this article for any changes to our betting analysis ahead of Cubs vs. Astros on Monday May 15, 2023.

Cubs vs. Astros 2023 Game Info

Monday's matchup between the Astros and Cubs at Minute Maid Park is scheduled to begin at 8:10PM ET.

• Who: Chicago Cubs vs. Houston Astros
• Date: Monday May 15, 2023
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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Make Informed Sports Betting Decisions with Dimers

Dimers' picks and predictions are based on 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Cubs vs. Astros predictions can help you make informed decisions, it's vital that you gamble responsibly and manage your finances effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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In addition to MLB picks and predictions, we also provide the best MLB prop bets for today, projecting home runs, RBIs, and more against the top odds available every single day of the MLB season.

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the World Series, with our data-led probabilities matched against the best odds available.