Cowboys vs. 49ers Week 5 Prediction and Odds - October 8, 2023

The San Francisco 49ers will square off with the Dallas Cowboys in NFL Week 5 action at Levi's Stadium on Sunday, commencing at 8:20PM ET.

Dimers' free betting picks for Cowboys vs. 49ers, plus our score prediction, betting odds and touchdown scorer probabilities, are featured in this article.

This Dallas vs. San Francisco betting analysis is sponsored by Bet365, which has a great Bet $5, Get $150 in Bonus Bets promo for new users.

Who Will Win: Cowboys vs. 49ers

Based on state-of-the-art machine learning and data, Dimers.com has simulated Sunday's Cowboys-49ers NFL game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the 49ers a 64% chance of getting the W against the Cowboys in Week 5 of the NFL season.

More: Cowboys vs. 49ers Simulated 10K Times

Cowboys vs. 49ers Odds

• Spread: 49ers -3.5 (-105), Cowboys +3.5 (-115)
• Moneyline: 49ers -180, Cowboys +152
• Total: Over/Under 45 (-110/-105)

The 49ers are -3.5 favorites versus the Cowboys, with -105 at PointsBet the best odds currently available.

For the underdog Cowboys (+3.5) to cover the spread, PointsBet also has the best odds currently on offer at -115.

PointsBet currently has the best moneyline odds for the 49ers at -180, which means you can risk $180 to win $100, for a total payout of $280, if they get the W.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Cowboys at +152, where you can bet $100 to profit $152, earning a total payout of $252, if they win.

The Over/Under sits at 45 with PointsBet, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check all the online sportsbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Cowboys and 49ers have a 50% chance of covering the spread, while the Over/Under total of 45 points also has an equal 50-50 chance of hitting.

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More: Free Prop Picks

Best Bets: Cowboys vs. 49ers

• Spread: 49ers -3.5 @ -105 via PointsBet (50% probability)
• Moneyline: 49ers @ -180 via PointsBet (64% probability)
• Total: Under 45 @ -105 via DraftKings Sportsbook (50% probability)

Dimers' best bets are based on world-class simulations and gambling expertise to help you make better decisions with the legal sportsbooks in the United States.

Cowboys vs. 49ers Prediction

Dimers.com's predicted final score for Dallas vs. San Francisco at Levi's Stadium in Week 5 has the 49ers prevailing 24-20.

Click or tap on See Matchup for more information.

Dimers has full coverage of this week's Cowboys-49ers game in Week 5, including pregame predictions, computer picks, and live updates.

Cowboys vs. 49ers Player Props

Who will score an anytime touchdown in Cowboys vs. 49ers? The latest data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Cowboys and 49ers, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you discover the best prop bets for Sunday's game.

According to DimersBOT, San Francisco's Christian McCaffrey is most likely to score the first TD in Cowboys vs. 49ers.

DimersBOT gives McCaffrey a 20.1% chance of scoring the first TD at Levi's Stadium, while the 49ers RB is a 68.8% chance of reaching the end zone at any point in the game.

Scroll down for our full list of first and anytime TD scorer probabilities, which provide a great avenue for you to use this DraftKings Sportsbook offer, which unlocks $200 in bonus bets from a $5 bet on any of the below players.

First Touchdown Scorer Probabilities

Dallas Cowboys

• Tony Pollard: 10.6% probability
• CeeDee Lamb: 9.8% probability
• Jake Ferguson: 6.3% probability
• Michael Gallup: 4.3% probability
• Brandin Cooks: 4.3% probability

San Francisco 49ers

• Christian McCaffrey: 20.1% probability
• Brandon Aiyuk: 8.6% probability
• Deebo Samuel: 7.7% probability
• George Kittle: 6.8% probability
• Jordan Mason: 3.1% probability

Anytime Touchdown Scorer Probabilities

Dallas Cowboys

• Tony Pollard: 43.9% probability
• CeeDee Lamb: 41.4% probability
• Jake Ferguson: 28.0% probability
• Brandin Cooks: 21.2% probability
• Michael Gallup: 20.4% probability

San Francisco 49ers

• Christian McCaffrey: 68.8% probability
• Brandon Aiyuk: 38.4% probability
• Deebo Samuel: 34.2% probability
• George Kittle: 30.7% probability
• Jordan Mason: 14.8% probability

Cowboys-49ers Projected Player Stats

Of the starting quarterbacks, the Cowboys' Dak Prescott is projected for 223 passing yards. The 49ers' Brock Purdy is expected to throw for 249 yards.

Cowboys Starting QB

• Dak Prescott: 223 projected yards

49ers Starting QB

• Brock Purdy: 249 projected yards

Cowboys Rushing

• Tony Pollard: 66 projected yards
• Rico Dowdle: 18 projected yards
• Dak Prescott: 13 projected yards

49ers Rushing

• Christian McCaffrey: 107 projected yards
• Jordan Mason: 22 projected yards
• Deebo Samuel: 11 projected yards

Cowboys Receiving

• CeeDee Lamb: 71 projected yards
• Brandin Cooks: 49 projected yards
• Michael Gallup: 36 projected yards
• Jake Ferguson: 35 projected yards
• Tony Pollard: 21 projected yards

49ers Receiving

• Brandon Aiyuk: 74 projected yards
• Deebo Samuel: 49 projected yards
• George Kittle: 48 projected yards
• Christian McCaffrey: 33 projected yards
• Jauan Jennings: 12 projected yards

Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting analysis before Cowboys vs. 49ers on Sunday October 8, 2023.

Cowboys vs. 49ers 2023

The NFL Week 5 game between the 49ers and Cowboys at Levi's Stadium is scheduled to commence at 8:20PM ET.

• Who: Dallas Cowboys vs. San Francisco 49ers
• Date: Sunday October 8, 2023
• Time: 8:20PM ET / 5:20PM PT
• Venue: Levi's Stadium

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Make Informed Sports Betting Decisions Today

Dimers' predictions are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods.

While our Cowboys vs. 49ers picks can help you make informed decisions, it's important that you gamble responsibly and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

What Other NFL Games Are on Today?

The Cowboys and 49ers aren't the only two NFL teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single NFL game via our NFL predictions. Not only do we provide with you quality predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Check it out now!

In addition to our leading NFL predictions, we also feature the best NFL prop bets today, projecting passing yards, touchdowns, and more against the best odds available every day of the NFL season.