Colts vs. Broncos Week 5 Prediction and Odds - Oct 6, 2022

The Denver Broncos and Indianapolis Colts lock horns in Week 5 of the NFL season at Empower Field at Mile High on Thursday, with kickoff at 8:15PM ET.

Dimers' free betting picks for Colts vs. Broncos, as well as game predictions, betting odds and projected player stats, are detailed in this article.

This Indianapolis vs. Denver betting analysis is sponsored by FanDuel Sportsbook, which has a No Sweat First Bet promo up to $1,000 for new users.

Who will win Colts vs. Broncos?

Based on cutting-edge machine learning and data, Dimers.com has simulated Thursday's Colts-Broncos NFL matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Broncos a 64% chance of beating the Colts in Week 5 of the NFL season.

More: Colts vs. Broncos Simulated 10,000 Times

Colts vs. Broncos Odds

• Spread: Broncos -3.5 (-104), Colts +3.5 (-115)
• Moneyline: Broncos -179, Colts +155
• Total: Over/Under 42 (-105/-110)

Point Spread, Moneyline and Over/Under

The Broncos are listed as -3.5 favorites against the Colts, with -104 at FanDuel Sportsbook the best odds currently available.

For the underdog Colts (+3.5) to cover the spread, PointsBet has the best odds currently on the market at -115.

Caesars Sportsbook currently has the best moneyline odds for the Broncos at -179. That means you can risk $179 to win $100, for a total payout of $279, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Colts at +155, where you can put down $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under for total points scored sits at 42 with PointsBet, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Colts and Broncos are a 50% chance of covering the spread, while the Over/Under total of 42 points is also considered an equal 50-50 chance of hitting.

More: Best Bets for Every NFL Matchup

Best Bets for Colts vs. Broncos

• Spread: Broncos -3.5 @ -104 via FanDuel Sportsbook (50% probability)
• Moneyline: Broncos @ -179 via Caesars Sportsbook (64% probability)
• Total: Over 42 @ -105 via PointsBet (50% probability)

Our best bets are based on detailed modeling and wagering expertise to bring you the best possible plays every day of the year.

Colts vs. Broncos Prediction

Dimers.com's predicted final score for Indianapolis vs. Denver at Empower Field at Mile High in Week 5 has the Broncos winning 22-19.

Click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's Colts-Broncos matchup in Week 5, including pregame predictions, computer picks, and live win probabilities.

Colts vs. Broncos Player Props

Who will score an anytime touchdown in Colts vs. Broncos? The latest data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Colts and Broncos, as well as player stat projections.

And you know what, we provide this information to you for FREE to help you select the best prop picks for Thursday's game.

According to DimersBOT, Denver's Melvin Gordon is most likely to score the first touchdown in Colts vs. Broncos.

DimersBOT gives Gordon a 13.9% chance of scoring the first TD at Empower Field at Mile High, while the Broncos RB is a 51.3% chance of registering an anytime touchdown.

Scroll down for the full list of first and anytime TD scorer probabilities.

First Touchdown Scorer Probabilities

Indianapolis Colts

• Nyheim Hines: 12.3% probability
• Michael Pittman: 6.9% probability
• Alec Pierce: 4.8% probability
• Phillip Lindsay: 4.6% probability
• Mo Alie-Cox: 4.2% probability

Denver Broncos

• Melvin Gordon: 13.9% probability
• Courtland Sutton: 10.7% probability
• Jerry Jeudy: 9.8% probability
• Mike Boone: 6.0% probability
• Russell Wilson: 4.7% probability

Anytime Touchdown Scorer Probabilities

Indianapolis Colts

• Nyheim Hines: 47.8% probability
• Michael Pittman: 29.4% probability
• Alec Pierce: 20.9% probability
• Mo Alie-Cox: 20.2% probability
• Phillip Lindsay: 20.1% probability

Denver Broncos

• Melvin Gordon: 51.3% probability
• Courtland Sutton: 41.8% probability
• Jerry Jeudy: 40.7% probability
• Mike Boone: 24.4% probability
• Russell Wilson: 21.2% probability

Colts-Broncos Projected Player Stats

Of the starting quarterbacks, the Colts' Matt Ryan is projected for 258 passing yards, while the Broncos' Russell Wilson is expected to throw for 246 yards.

Colts Starting QB

• Matt Ryan: 258 projected yards

Broncos Starting QB

• Russell Wilson: 246 projected yards

Colts Rushing

• Nyheim Hines: 46 projected yards
• Phillip Lindsay: 30 projected yards
• Deon Jackson: 11 projected yards

Broncos Rushing

• Melvin Gordon: 64 projected yards
• Mike Boone: 33 projected yards
• Russell Wilson: 17 projected yards

Colts Receiving

• Michael Pittman: 64 projected yards
• Nyheim Hines: 32 projected yards
• Alec Pierce: 31 projected yards
• Ashton Dulin: 25 projected yards
• Kylen Granson: 23 projected yards

Broncos Receiving

• Courtland Sutton: 64 projected yards
• Jerry Jeudy: 56 projected yards
• KJ Hamler: 15 projected yards
• Albert Okwuegbunam: 14 projected yards
• Melvin Gordon: 13 projected yards

Remember, DimersBOT updates regularly, so keep an eye on this page for the latest betting analysis before Colts vs. Broncos on Thursday October 6, 2022.

Colts vs. Broncos 2022

The NFL Week 5 action between the Broncos and Colts at Empower Field at Mile High is scheduled to commence at 8:15PM ET.

• Who: Indianapolis Colts vs. Denver Broncos
• Date: Thursday October 6, 2022
• Time: 8:15PM ET / 5:15PM PT
• Venue: Empower Field at Mile High

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