Rockies vs. Padres Prediction: San Diego Predicted to Win Friday's MLB Matchup [4/11/2025]

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Written by Dave Garofolo

Our expert prediction for Friday's Colorado Rockies vs San Diego Padres matchup.

Colorado Rockies-San Diego Padres Predictions and Game Preview.
PETCO Park sets the stage for the MLB matchup between the Colorado Rockies and San Diego Padres this Friday.

MLB action continues on Friday at 9:40PM ET as the Colorado Rockies lock horns with the San Diego Padres at PETCO Park.

Nick Pivetta (1-1, 2.70 ERA) will get the ball for the Padres, pitting him against Germán Márquez (0-1, 2.46 ERA) for the Rockies.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Padres as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Colorado-San Diego game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Padres' chance of winning is 65%, while the Rockies' is 35%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Rockies vs. Padres predictions page.

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Rockies vs. Rockies Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Friday's MLB game between the Rockies and Padres 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Padres a 65% chance of defeating the Rockies.

According to our model, the Rockies (+1.5) have a 56% chance of covering the run line, while the over/under total of 7.5 runs has a 54% chance of staying under.

Pre-Game Probabilities
Last Updated: 1:28AM, Apr 12
Moneyline
Over / Under
Run Line
Rockies
Win %
35%
65%
Get the best bets with Dimers Pro
See Matchup
Padres
Rockies COL
Win %
35%
65%
See Matchup
Padres SD
Germán Márquez 0-1, 2.46 ERA
Nick Pivetta 1-1, 2.70 ERA
Get the best bets with Dimers Pro

Rockies vs. Padres Odds [4/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Rockies Padres
Run Line +1.5 (-118) -1.5 (+105)
Moneyline +185 -200
Total o7.5 (-105) u7.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Rockies vs. Padres Picks and Best Bets

Our model's biggest edge in today's Rockies vs. Padres matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Rockies vs. Padres Game-Day Updates and Essential Details

Friday's MLB matchup between the Padres and Rockies at PETCO Park is scheduled to start at 9:40PM ET.

Dimers.com's full preview of Friday's Rockies vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Colorado vs. San Diego picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Padres, with a 65% win probability, will likely beat the Rockies on Friday.

AI and automation have enhanced this article to quickly deliver accurate Rockies vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most accurate probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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