College Basketball and March Madness Picks Today: Saturday's Best Bets Include UCLA vs. Tennessee Play [3/22/2025]

College basketball betting is back for another pulse-pounding slate on 3/22, and we're here to serve up our top picks for Saturday's NCAAM action, with our model working hard to find bets in the March Madness tournament and elsewhere.

Today's college basketball best bets come from a range of matchups, including the UCLA vs. Tennessee game at 9:40PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Featuring a standout spread play with an edge of 5.2%, these picks are powered by data-driven simulations and machine learning.

For unlimited access to everything Dimers has to offer on Saturday, March 22, 2025—including our full set of March Madness picks and best bets—check out Dimers Pro.

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List of College Basketball Picks Tonight [3/22, Updated: 9:31PM ET]

After digging deep into the numbers and conducting thousands of simulations, our independent predictive analytics model has figured out the best college basketball bets for Saturday, March 22, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro users.

UCLA +5.5 (-112)

• Edge: 5.2%
• Probability: 58%
• Matchup: UCLA vs. Tennessee (9:40PM ET, Saturday)

Our model has pinpointed the next college basketball betting opportunity tonight, which comes in the UCLA vs. Tennessee March Madness matchup. We recommend a spread bet on UCLA +5.5 at -112 odds, offering an edge of 5.2%.

UCLA vs. Tennessee Over 131.5 Points (-105)

• Edge: 2.5%
• Probability: 53.7%
• Matchup: UCLA vs. Tennessee (9:40PM ET, Saturday)

Our model has found another great college basketball bet for Saturday's NCAA action, again in the March Madness matchup between UCLA and Tennessee. We suggest placing an over/under wager on Over 131.5 Points at -105 odds, with our analysis showing a compelling 2.5% edge.

MORE: March Madness Props

NCAAM Best Bets: Saturday, 3/22/2025

As of 9:31PM ET, here are the next two college basketball bets recommended by our model:

Matchup	Bet	Odds	Edge
UCLA vs. Tennessee	UCLA +5.5	-112 @ DraftKings	5.2%
UCLA vs. Tennessee	Over 131.5 Points	-105 @ BetMGM	2.5%

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Among Saturday's college basketball picks is a -105n over/under play with an edge of 2.1%.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for March 22, 2025.

List of Upcoming College Basketball Games To Bet On

• UCLA vs. Tennessee (9:40PM ET, Saturday)
• Connecticut vs. Florida (12:10PM ET, Sunday)
• Army vs. Elon (2:30PM ET, Sunday)
• Baylor vs. Duke (2:40PM ET, Sunday)
• Oklahoma State vs. SMU (3:00PM ET, Sunday)
• Illinois vs. Kentucky (5:15PM ET, Sunday)
• Saint Mary's vs. Alabama (6:10PM ET, Sunday)
• Arkansas State vs. North Texas (7:00PM ET, Sunday)
• Loyola Chicago vs. San Francisco (7:00PM ET, Sunday)
• Colorado State vs. Maryland (7:10PM ET, Sunday)

More About CBB

This article is part of our college basketball player props and college basketball best bets series.

For more NCAAB betting content, we have college basketball betting news and the latest March Madness odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.